Tris(cyclopentadienyl)lanthanide Complexes as Catalysts for Hydroboration Reaction toward Aldehydes and Ketones

Sufang Chen†, Dandan Yan†, Mingqiang Xue^*（薛明强）, Yubiao Hong, Yingming Yao^*（姚英明）, and Qi Shen^*（沈琪）

Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Dushu Lake Campus, Soochow University, Suzhou 215123, People’s Republic of China

Org. Lett., 2017, 19 (13), 3382--3385

It was found that homoleptic cyclopentadienyl lanthanide complexes Cp₃Ln (Ln = Y (1), Yb (2), Sm (3), Nd (4), La (5), Cp = cyclopentadienyl) can be employed as excellent catalysts for the hydroboration of various aldehydes and ketones toward pinacolborane. These robust lanthanide catalysts exhibited high reactivity with low catalyst loadings (0.01–1 mol %) under mild conditions and good functional group tolerability. These complexes also demonstrated uniquely carbonyl-selective hydroboration in the presence of alkenes and alkynes.

链接：http://pubs.acs.org/doi/abs/10.1021/acs.orglett.7b01335