Synthesis of star-glycopolymers by Cu(0)-mediated radical polymerisation in the absence and presence of oxygen
Hui Xue‡a, Lun Peng‡b, Yishi Dong a, Yuqing Zheng b, Yafei Luan a, Xiang Hu a,Gaojian Chen*ab（陈高健）and Hong Chen*a（陈红）
aState and Local Joint Engineering Laboratory for Novel Functional Polymeric Materials, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, 199 Ren'ai Road, Suzhou 215123, P. R. China.
bCenter for Soft Condensed Matter Physics and Interdisciplinary Research, Soochow University, Suzhou 215006, P. R. China.
RSC Adv., 2017, 7, 8484–8490
In this paper, novel star glycopolymers were synthesized via Cu(0)-mediated radical polymerisation at ambient temperature. The reaction was fast with little star-star coupling. Moreover, star glycopolymers can be obtained without removing oxygen from the polymerisation mixture. The effects of solvent and the ratio of initiator/catalyst/ligand on polymerisation were investigated, and the optimal conditions for the synthesis of star glycopolymer were determined. In addition, the binding ability between synthesised glycopolymers and concanavalin A (ConA) was studied using a turbidity test and quartz crystal microbalance-dissipation (QCM-D). Compared with linear glycopolymers, star glycopolymers showed higher binding ability to specific lectins and the strongest binding was obtained when the molecular weight was medium.
链接：http://pubs.rsc.org/en/content/articlepdf/2017/RA/C6RA28763H