Photocatalyst- and Transition-Metal-Free Visible-Light-Promoted Intramolecular C(sp2 )−S Formation
Hao Wang1, Qi Wu1, Jian-Dong Zhang1, *（章建东）, Hai-Yan Li2, and Hong-Xi Li1 ,*（李红喜）
1 College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, China
2 Analysis and Testing Center, Soochow University, Suzhou 215123, China
Org. Lett.2021, 23, 2078--2083
A photocatalyst- and transition-metal-free visible-light-induced cyclization of ortho-halothiobenzanilides has been developed. Upon irradiation with visible light, substrates undergo dehalogenative cyclization to 2-aryl benzothiazoles with high efficiency and selectivity. This photocyclization exhibits a high tolerance to various functional groups, is applicable for the synthesis of 2-alkyl benzothiazoles, and is easy to set up for gram-scale reaction.
链接：https://pubs.acs.org/doi/abs/10.1021/acs.orglett.1c00235
