Cu(II)/Ag(I)-Catalyzed Cascade Reaction of Sulfonylhydrazone with Anthranils: Synthesis of 2-Aryl-3-sulfonyl Substituted Quinoline Derivatives

Fei Wang，Pei Xu，Shun-Yi Wang^*（汪顺义）, andShun-Jun Ji^*（纪顺俊）

Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science & Collaborative Innovation Center of Suzhou Nano Science and Technology,Soochow University,Suzhou215123,China

Org. Lett.,2018,20(8), 2204--2207

In this paper, a Cu(II)/Ag(I)-catalyzed cascade reaction of anthranils with sulfonylhydrazone to construct 2-phenyl-3-sulfonyl disubstituted quinoline derivatives under mild conditions was studied. The mechanism study indicated that this reaction involves radical addition, and new C–C, C–N, and C–S bonds were constructed in one step.

链接：https://pubs.acs.org/doi/10.1021/acs.orglett.8b00525