黄志斌教授与赵应声副教授合作在Org. Chem. Front. 上发表研究论文

作者: 发布时间:2016-12-23 浏览次数:676

Ru-Catalyzed selective C–H oxidative olefination with N-heteroarenes directed by pivaloyl amide

Li Zhang,a   Changpeng Chen,a   Jian Han,a   Zhi-Bin Huang*a (黄志斌)and   Yingsheng Zhao*a (赵应声)

 

 a Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, China

 

Org. Chem. Front., 2016,3, 1271-1275

 

A highly efficient and practical Ru-catalyzed direct C–H functionalization of indolines and N-alkylaniline with a simple pivaloyl as a directing group is developed. Broad substrate scopes with respect to N-heteroarenes and olefins are observed. The selective C7-position alkynylation for indoline also proceeds well by using inexpensive ruthenium as a catalyst, and pivaloyl as a directing group.

 

              

 

链接:http://pubs.rsc.org/en/Content/ArticleLanding/2016/QO/C6QO00327C#!divAbstract