汪顺义教授与纪顺俊教授合作在Org. Chem. Front. 上发表研究论文

作者: 发布时间:2016-11-16 浏览次数:771

An isocyanide insertion approach to substituted pyrrolo[2,3-b]quinolines under metal-free and azide-free conditions

Cheng-Guo Liu,a   Zheng-Yang Gu,a   Hui-Wen Bai,a  Shun-Yi Wang*a (汪顺义)and   Shun-Jun Ji*a (纪顺俊)

 

aKey Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science & Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou

 

Org. Chem. Front., 2016,3, 1299-1303

 

A new strategy for the catalytic synthesis of the pyrrolo[2,3-b]quinoline skeleton by the reaction of isocyanides with (cyclopropylidene(aryl)methyl)aniline (amino-MCPs) is presented, taking advantage of I2/CHP mediated carbodiimide intermediate generation. This reaction involves three C–N bonds and one C–C bond generation under metal-free and azide-free conditions.

 

                       

 

链接:http://pubs.rsc.org/en/content/articlelanding/2016/qo/c6qo00373g#!divAbstract