黄智豪副研究员与张正彪教授合作在 Macromolecules 上发表研究论文

A Versatile Synthetic Platform for Discrete Oligo- and Polyesters Based on Optimized Protective Groups Via Iterative Exponential Growth

Suhua Duan1, Xiaojie Yang1, Ze Yang3, Yuxin Liu1, Qiunan Shi1, Zhilin Yang1, Haibing Wu1, Yue Han1, Yongquan Wang1, Hang Shen1, Zhihao Huang1,*(黄智豪), Xue-Hui Dong3, Zhengbiao Zhang(张正彪)1,2, *


1 College of Chemistry, Chemical Engineering and Materials Science, Soochow University, 215123 Suzhou,China

2 State Key Laboratory of Radiation Medicine and Protection, Soochow University, 215123Suzhou, China

3 South China Advanced Institute for SoftMatter Science and Technology, South China University ofTechnology, 510640 Guangzhou, China


Macromolecules 2021, 54, 23, 10830--10837


Discrete oligo- and polyesters are highly attractive for a wide range of investigations because of their great fidelity on structure–property relationships. Even though numerous synthetic approaches have been developed, a more versatile synthetic platform with broad group tolerance is still desired. Herein, we report an iterative exponential growth strategy for efficient synthesis of discrete oligo- and polyesters, employing an optimized protective group pair, namely, TBDPS ether and t-butyl ester. The versatility of the strategy is demonstrated by facile preparation of several structurally diverse discrete oligo- and polyesters under mild, safe, and scalable reaction conditions, with the number of repeat units up to 256. Moreover, the contributions of the terminal protective groups on the melting and crystallization behaviors of discrete oligo- and poly(ε-caprolactone)s were investigated. With this robust synthetic platform, various functional moieties can be readily incorporated into polyester chains, and a myriad of applications of polyesters could thus be reasonably anticipated.

  


链接:https://pubs.acs.org/doi/abs/10.1021/acs.macromol.1c01498