朱晨教授在Angew.Chem.Int.Ed. 上发表研究论文

Zhen Wu^a, Rongguo Ren^a, and Chen Zhu^ab*（朱晨）

^aKey Laboratory of Organic Synthesis of Jiangsu Province

College of Chemistry, Chemical Engineering and Materials Science

Soochow University，199 Ren-Ai Road, Suzhou, Jiangsu 215123 (China)

^bKey Laboratory of Synthetic Chemistry of Natural Substances

Shanghai Institute of Organic Chemistry Chinese Academy of Sciences，345 Lingling Road, Shanghai 200032 (China)

Angew.Chem.Int.Ed.，2016，55，10821-10824

A conceptually new, efficient, and metal-free approach for the challenging azidocyanation of unactivated alkenes is presented. The strategy of intramolecular distal cyano migration is combined with alkene difunctionalization for the first time. A variety of useful azido-substituted alkyl nitriles are prepared in good yields and, most importantly, with

exquisite regio- and stereo-selectivities.

链接：http://onlinelibrary.wiley.com/doi/10.1002/anie.201605130/abstract;jsessionid=63DF84B3FC858F11B66D6A18FB57BBC4.f01t04