报告题目Ⅰ：Poly-benzylic Ammonium Chloride Resins as Solid Catalysts forGlucose Dehydration to 5-Hydroxymethylfurfural

报告题目Ⅱ：Direct Benzylation of Malonates with Benzyl Alcohols – In Situ C-O Bond Activation

报 告 人:  曹雪琴副教授

报告时间:  2016年2月26日10:00 - 11:00

报告地点:  907-1549

个人简介:

2004-2009 苏州大学轻化工程系 博士

2006-2007 日本福井大学 访问学者

2013-2015 新加坡生物工程与纳米技术研究所 博士后

1996-今    苏州大学材料与化学化工学部 副教授

AbstractⅠ: An ammonium resin(PBnNH3Cl) was used as a sole catalyst for the glucose and polysaccharidesdehydration to 5-hydroxymethxylfurfural (HMF) in high selectivity (>80%) inDMSO or biphasic reaction system. The simple resin works as a dual functionalorganocatalyst to catalyze glucose isomerization and fructose dehydrationreactions. It represents the first sole catalyst and metal-free catalyticsystem for highly selective glucose dehydration to HMF in a mild condition.

AbstractⅡ：High step- and atomic-economy are the endlesspursuit in organic and pharmaceutical synthesis. Herein, a new method fordirectly coupling of benzyl/allyl alcohols with malonates via palladiumcatalyzed Tsuji-Trost type reaction was developed. The reaction was carriedinorganic carbonate solvent which would activate alcohols in situ, replacing the traditional pre-synthesized carbonates. Thenew process demonstrated high efficiency, high selectivity and high generality.A wide variety of mono-substituted and bis-substituted malonates wereselectively produced under different conditions, represents a more step- and atom-economicand environmentally benign synthetic protocol.