汪顺义教授在 Org. Lett. 上发表研究论文

Metal-Free Chemoselective Reaction of Sulfoxonium Ylides and Thiosulfonates: Diverse Synthesis of 1,4-Diketones, Aryl Sulfursulfoxonium Ylides, and β‑Keto Thiosulfones Derivatives

Fei Wang, Bo-Xi Liu, Weidong Rao, and Shun-Yi Wang*(汪顺义)


1 Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science & Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou 215123, China

2 Jiangsu Provincial Key Lab for the Chemistry and Utilization of Agro-Forest Biomass, College and Chemical Engineering, Nanjing Forestry University, Nanjing 210037, China;


Org. Lett. 2020, 22, 6600--6604


A diverse chemoselective insertion reaction of sulfoxonium ylides and thiosulfonates under transition-metal-free conditions is developed, which successfully affords 1,4-diketone compounds, arylthiosulfoxide-ylides, and β-keto thiosulfones, respectively. The nucleophilic addition of two molecular sulfoxonium ylides to construct sulfone-substituted 1,4-dione compounds is the highlight of this work.




链接:https://pubs.acs.org/doi/10.1021/acs.orglett.0c02370