报告题目：Stimuli-ResponsivePolymer-Based Sensors, Muscles, and Drug Delivery Platforms
报告人：Prof. Michael J. Serpe (University of Alberta)
报告时间：2016年5月16日上午10：00-11：00
报告地点：独墅湖校区907-1445房间
【报告摘要】：
The group'sresearch is focused on the development of novel polymer-based materials forsolving environmental and health-related problems. To solve these problems, thegroup primarily employs poly (N-isopropylacrylamide)(pNIPAm)-based spherical particles as the active component in our technologies.PNIPAm-based particles (nano or microgels, depending on their diameter) areextremely porous, and are fully water soluble and swellable. Additionally,pNIPAm-based nano/microgels are responsive to temperature, shrinking indiameter as the temperature is increased to >32 °C and reswelling when theyare cooled to < 32 °C. Our group has exploited these properties for numerousapplications. Today's talk will highlight the group's work on the developmentof these devices for sensing and biosensing, as muscles, and forcontrolled/triggered drug delivery.
Bio: Prof.Michael J. Serpe received his B.S. at the University of CentralFlorida in 2000, and his Ph.D. in Analytical Chemistry from the GeorgiaInstitute of Technology in 2004. After conducting research in industry for oneyear he joined the group of Professor Stephen Craig at Duke University as aPostdoctoral Fellow. He joined the Department of Chemistry at the University of Alberta as an Assistant Professor in 2009and was awarded early tenure and promoted to Associate Professor in 2014. TheSerpe Group is studying various aspects of colloid, polymer, and surfacescience with emphasis on using photonic materials and responsive polymer-basedsystems for myriad applications. Some examples include sensing, biosensing,controlled/triggered drug delivery, self-bending materials and actuators (i.e.,artificial muscles), and water remediation. Prof. Serpe was recently appointed(April 2016) as an Associate Scientific Director and Theme Lead for theCanadian National Centre of Excellence IC-IMPACTS. Prof. Serpe is also Chair ofthe local section of the Chemical Institute of Canada, and is a member of theexecutive committees for the Analytical and Materials Chemistry Divisions ofthe Chemical Institute of Canada. Prof. Serpe has been granted a University ofAlberta Faculty of Science Research Fellowship, named a Grand Challenges CanadaRising Star in Global Health, received the 2013 Petro Canada Young InnovatorAward, has been named one of Edmonton's Top 40 Under 40 by Avenue Magazine for2013-2014, received the 2015 Martha Cook Piper Research Prize, and the 2016Fred Beamish Award from the Canadian Society for Chemistry.
Representative group publications:
1) Islam, M.R.; Li, X.; Smyth, K.; Serpe, M.J."Polymer-Based Muscle Expansion and Contraction" Angew. Chem. Int. Edit., 2013, 52(39), 10330-10333.
2) "Polyelectrolyte Mediated Intra and Intermolecular Crosslinkingin Microgel-Based Etalons for Sensing Protein Concentration in Solution" Chem. Commun., 2013, 49,2646-2648.
3) Islam, M.R.; Serpe, M.J. " Penetration of Polyelectrolytes intoCharged Poly (N-isopropylacrylamide) Microgel Layers Confined Between TwoSurfaces" Macromolecules, 2013,46 (4), 1599–1606.
4) Sorrell, C.D.; Carter, M.C.D.; Serpe, M.J. "Color Tunable Poly (N-Isopropylacrylamide)-co-Acrylic AcidMicrogel/Au Hybrid Assemblies" Adv.Funct. Mater., 2011, 21, 425-433.