A novel and convenient synthesis of 4-hydroxy-6-methyl-3-(1-(phenylimino) ethyl)-2H-pyran-2-one deri
A novel and convenient synthesis of 4-hydroxy-6-methyl-3-(1-(phenylimino) ethyl)-2H-pyran-2-one derivatives under ultrasound irradiation - Huiyan Wang , Yi Zou , Xuan Zhao , Daqing Shi*
- Ultrason. Sonochem., 2011, 18, 1048-1051.
A facile, efficient and environment-friendly protocol for the synthesis of 4-hydroxy-6-methyl-3-(1-(phenylimino)ethyl)-2H-pyran-2-one derivatives has been developed by the convenient ultrasound-mediated condensation of amine with dehydroacetic acid. This method provides several advantages over current reaction methodologies including a simple work-up procedure, shorter reaction times and higher yields.
