Nickel-catalyzed direct C-H arylation of unactivated arenes with aryl halides

Nickel-catalyzed direct C-H arylation of unactivated arenes with aryl halides+

Guanlei Xie,Tingyi Li,Xiaoming Qu,Jincheng Mao*
J. Mol. Catal. A: Chem. 2011, 339, doi:10.1016/j.molcata.2011.03.007

Readily available Ni(OAc)₂·4H₂O could catalyze direct C–H arylation of unactivated arenes with aryl bromides/iodides in presence of 1,10-phenanthroline as the ligand without using any additives. This protocol makes C–H arylation more practical and useful.