邓超 (Deng Chao)
Professor (Polymer Chemistry)
Ph.D. Changchun Institute of Applied Chemistry, Chinese Academy of Sciences (2001-2006)
Postdoc, University of Ottawa (2006-2010)
Tel: 86-512-65884933 (o)
Fax: 86-512-65884933
Email: cdeng@suda.edu.cn
Research Interests: biomedical polymers, polypeptide nanosystems, injectable microgels/hydrogels, drug/nucleic acid targeted delivery, arterial embolization therapy, cancer immunotherapy.
学历及学术经历:邓超，苏州大学教授，博导。江苏省先进功能高分子材料重点实验室副主任，苏州大学-博瑞医药创新靶向药物研究院副院长，全球高被引科学家，国际先进材料学会（IAAM）会士。2006年中科院长春应用化学所获博士学位，2006-2010年加拿大渥太华大学眼睛所、心脏所和细胞分子生物医学系博士后，期间曾获加拿大心脏及中风基金委研究奖学金，渥太华心脏研究所分子功能和图像研究奖学金。2010年6月起受聘为苏州大学副教授，2014年晋升为教授。在国际主流期刊如Nat. Sustain., Nat. Biomed. Eng., Nat. Commun., ACS Nano, Adv. Mater., Adv. Funct. Mater., Prog. Polym. Sci., Biomaterials, Chem. Mater., J. Control. Release, Macromolecules等上发表论文160多篇，被引用13000多次，H-因子61。多篇论文被MaterialsViewChina，中国聚合物网和高分子科技等作为研究亮点进行专题报道。申请中国发明专利21项和国际发明专利2项，授权中国发明专利15项。担任六届“新型高分子材料与控制释放国际会议”（SIPCD 2010, 2012, 2014, 2016, 2018，2024）”的秘书长，Front. Chem.、Nanomaterials等多个学术期刊的编辑或编委。主持七项国家自然科学基金项目，参与多项国家重点研发计划项目和国际合作项目。
研究领域: 生物医用高分子材料、聚多肽纳米药物载体、可注射性微凝胶/水凝胶、药物/核酸靶向递送、动脉栓塞治疗，肿瘤免疫治疗等。
Main Publications
1.Z.L. Huang, Y. Wang, J.K. Guo, S.H. Lv, J. Gui, Z.Y. Zhong*, J. Chen*, and C. Deng*, Versatile and potent insecticide scavengers based on locust cell membrane-adapted mesoporous silica microparticles to protect managed pollinators, Nat. Sustain. 2026, In press
2.Q.Z. Ren, X.F. Zhao, L.L. Zhou, R.N. Ye, L.G. Chen, K.Y. Ren, X.J. Piao, Y.H. Zhou, Y.M. Qi, L. Cao, K. Chan, L. Du, P. Gao, B. Ying, C. Deng, F.H. Meng, F.F. Zhou*, C.C. Xu*, and Z.Y. Zhong*, Polymer-mRNA complexes for monocyte trafficked, lymph node targeted cancer vaccination, Nat. Biomed. Eng. 2026, In press.
3.J.K. Guo, J.T. Huang, Y. Wang, J. Sun, S. Liu, C. Deng*, J. Lu*, and Z.Y. Zhong*, Absorbable microspheres co-delivering HIF-1α inhibitor augment transarterial chemoembolization by reversing tumor hypoxia and immunosuppression, Acta Biomater. 2026, DOI: 10.1016/j.actbio.2026.03.005.
4.Y. Wang, J.K. Guo, D. Hu, H.J. Tan, W.T. Chen, C. Deng*, X.L. Zhu*, and Z.Y. Zhong*, Absorbable microspheres sustaining epirubicin and TLR7 agonist release for Transarterial chemo-immuno-embolization in liver tumor, J. Control. Release 2026, 390, 114576.
5.J.K. Guo, J.T. Huang, Z.L. Huang, J. Sun, Y. Wang, H.J. Tan, D. Hu, C. Deng*, X.L. Zhu*, and Z.Y. Zhong*, Persistent and potent anticancer immunity empowered by manganese-coordinated STING-activating microgels, Adv. Func. Mater. 2026, 16, e21279.
6.J.K. Guo, J.T. Huang, Z.L. Huang, D. Hu, H.J. Tan, Y. Wang, C. Deng*, X.L. Zhu*, and Z.Y. Zhong*, Tumor vessel-adaptable adhesive and absorbable microspheres for sustainable Transarterial chemoembolization therapy, Nat. Commun. 2025, 16, 6239.
7.K. Huang, Y.P. Liu, H. Miao, Y.W. Li, Q.Y. Fan, H.Y. Zhang, C.J. Zuo, J.F. Zhu, Q.J. Zheng, C. Deng*, Z.H. Sun*, and Z.B. Tong*, Nebulized lipid nanoparticles based on degradable ionizable glycerolipid for potent pulmonary mRNA delivery, ACS Nano 2025, 19, 1128-1139.
8.X.F. Zhao, Y.Y. Zhang, X. Wang, Z.M. Fu, Z.Y. Zhong*, and C. Deng*, Multivalent ionizable lipid-polypeptide for tumor-confined mRNA transfection, Bioact. Mater. 2025, 46, 423-433.
9.K. Huang, N. Li, Y.W. Li, J.F. Zhu, Q.Y. Fan, J.L. Yang, Y.J. Gao, Y.P. Liu, S.F. Gao, P. Zhao, K. Wei, C. Deng*, C.J. Zuo*, and Z.H. Sun*, Circular mRNA vaccine against SARS-cov-2 variants enabled by degradable lipid nanoparticles, ACS Appl. Mater. Interfaces 2025, 17, 4699-4710.
10.Y.Y. Zhang, X.F. Zhao, X. Wang, S.Y. Wang, Z.Y. Zhong*, and C. Deng*, Polypeptide nanomicelles co-deliver PLK1 and BCL-2/xL inhibitors for synergetic therapy of brain tumor, Nano Today 2025, 62, 102712.
11.J.K. Guo, H.J. Tan, W.T. Chen, Y. Wang, W.H. Lin, Z.Y. Zhong*, and C. Deng*, Oncolytic microgels with regulated antibody release augment tumor immunotherapy, J. Control. Release 2025, 385, 114003.
12.H.J. Tan, J.K. Guo, Y. Wang, W.T. Chen, Z.Y. Zhong*, and C. Deng*, Long-acting in situ cancer vaccines by oncolytic STING-activating microgels, Small 2025, e03561.
13.X.F. Zhao, C. Deng*, and Z.Y. Zhong*, Polypeptide for drug delivery, Biomater. Sci. J. Phys. Mater. 2024, 7, 012502.
14.R. Chen, J.K. Yang, Y.M. Mao, X.F. Zhao, R. Cheng*, C. Deng*, and Z.Y. Zhong*, Antibody-mediated nanodrug of proteasome inhibitor carfilzomib boosts the treatment of multiple myeloma, Biomacromolecules 2023, 24, 5371-5380.
15.J.G. Xie, X.F. Zhao, P. Zhang, Y.Y. Zhang, R. Cheng, Z.Y. Zhong*, and C. Deng*, Codelivery of BCL2 and MCL1 inhibitors enabled by phenylboronic acid-functionalized polypeptide nanovehicles for synergetic and potent therapy of acute myeloid leukemia, Adv. Sci. 2023, 2204866.
16.Y.Y. Liu, J.G. Xie, X.F. Zhao, Y.Y. Zhang, Z.Y. Zhong*, and C. Deng*, A polymeric IDO inhibitor based on poly(ethylene glycol)-b-poly(L-tyrosine-co-1-methyl-D-tryptophan) enables facile trident cancer immunotherapy, Biomater. Sci. 2022, 10, 5731.
17.Q. Zhang, Y.Y. Liu, Y.C. Fei, J.G. Xie, X.F. Zhao, Z.Y. Zhong*, and C. Deng*, Phenylboronic acid-functionalized copolypeptides: Facile synthesis and responsive dual anticancer drug release, Biomacromolecules. 2022, 23, 2989-2998.
18.Z.Q. Zhang, Q. Zhang, J.G. Xie, Z.Y. Zhong*, and C. Deng*, Enzyme-responsive micellar JQ1 induces enhanced BET protein inhibition and immunotherapy of malignant tumors, Biomater. Sci. 2021, 9, 6915-6926.
19.J. Ouyang, Y. Jiang, C. Deng, Z.Y. Zhong*, and Q. Lan*, Doxorubicin delivered via ApoE-directed reduction-sensitive polymersomes potently inhibit orthotopic human glioblastoma xenografts in nude mice, Int. J. Nanomedicine2021, 16, 4105-4115.
20.Q.Y. Fan, Y.Y. Liu, G.H. Cui, Z.Y. Zhong*, and C. Deng*, Brain delivery of Plk1 inhibitor via chimaeric polypeptide polymersomes for safe and superb treatment of orthotopic glioblastoma, J. Control. Release2021, 329, 1139-1149.
21.C. Deng*,Q.Zhang, J.K. Guo, X.F. Zhao, and Z.Y. Zhong*, Robust and smart polypeptide-based nanomedicines for targeted tumor therapy, Adv. Drug Delivery Rev. 2020, 160, 199-211.
22.H.M. Fang, X.F. Zhao, X.L. Gu, H.L. Sun, R. Cheng, Z.Y. Zhong*, and C. Deng*, CD44-targeted multifunctional nanomedicines based on a single-component hyaluronic acid conjugate with all-natural precursors: construction and treatment of metastatic breast tumors in vivo, Biomacromolecules2020, 21, 104-113.
23.S. Li#, M. Qiu#, J.K. Guo, X.F. Zhao, Z.Y. Zhong*, and C. Deng*, Coating-sheddable CD44-targeted PLGA nanomedicines fabricated by using photo-click-crosslinkable surfactant, Adv. Therap.2020, 3, 1900160.
24.H.L. Sun, X.L. Gu, Q. Zhang, H. Xu, Z.Y. Zhong*, and C. Deng*, Cancer Nanomedicines Based on Synthetic Polypeptides, Biomacromolecules2019, 20, 4299-4311.
25.X.L. Gu, Z.H. Zhu, Q.Y. Fan, Y.H. Wei, G.L. Wang, F.H. Meng, Z.Y. Zhong*, and C. Deng*, Nanoagents based on poly(ethylene glycol)-b-poly(L-thyroxine) block copolypeptide for enhanced dual-modality imaging and targeted tumor radiotherapy, Small2019, 1902577.
26.X.L. Gu, Y.H. Wei, Q.Y. Fan, H.L. Sun, R. Cheng, Z.Y. Zhong*, and C. Deng*, cRGD-decorated biodegradable polytyrosine nanoparticles for robust encapsulation and targeted delivery of doxorubicin to colorectal cancer in vivo, J. Control. Release2019, 301, 110-118.
27.K. Huang, Y.H. He, Z.H. Zhu, J.K. Guo, G.L. Guang, C. Deng*, and Z.Y. Zhong*, Small, traceable, endosome-disrupting, and bioresponsive click nanogels fabricated via microfluidics for CD-targeted cytoplasmic delivery of therapeutic proteins, ACS Appl. Mater. Interfaces2019, 11, 22171-22180.
28.M. Qiu, J. Ouyang, Y.H. Wei, J. Zhang, Q. Lan, C. Deng*, and Z.Y. Zhong*, Selective cell penetrating peptide-functionalized envelope-type chimeric lipopepsomes boost systemic RNAi therapy for lung tumors, Adv. Healthcare. Mater.2019, 8, 1900500.
29.H.Z. Qin, Y. Jiang, J. Zhang, C. Deng*, and Z.Y. Zhong*, Oncoprotein inhibitor rigosertib loaded in apoe-targeted smart polymersomes reveals high safety and potency against human glioblastoma in mice, Mol. Pharmaceutics2019, 16, 3711-3719.
30.J. Chen, H. He, C. Deng*, L.C. Yin, and Z.Y. Zhong*, Saporin-loaded CD44 and EGFR dual-targeted nanogels for potent inhibition of metastatic breast cancer in vivo, Int.J. Pharm. 2019, 560, 57-64.
31.D. Kuraitis, K. Hosoyama, N. J. R. Blackburn, C. Deng, Z. Zhong*, E. J. Suuronen*, Functionalization of soft materials for cardiac repair and regeneration. Crit. Rev. Biotechnol.2019, 39, 451-468.
32.N. Rades, K. Achazi, M. Qiu, C. Deng, R. Haag, Z.Y. Zhong*, and K. Licha*, Reductively cleavable polymer-drug conjugates based on dendritic polyglycerol sulfate and monomethyl auristatin E as anticancer drugs, J. Control. Release2019, 300, 13-21.
33.M. Qiu, H.L. Sun, F.H. Meng, R. Cheng, J. Zhang, C. Deng*, and Z.Y. Zhong*, Lipopepsomes: A novel and robust family of nano-vesicles capable of highly efficient encapsulation and tumor-targeted delivery of doxorubicin hydrochloride in vivo, J. Control. Release2018, 272, 107-113.
34.M. Qiu, X.X. Wang, H.L. Sun, J. Zhang, C. Deng*, and Z.Y. Zhong*, Cyclic RGD-peptide-functionalized polylipopeptide micelles for enhanced loading and targeted delivery of monomethyl auristatin E, Mol. Pharmaceutics2018, 15, 4854-4861.
35.J. Chen, K. Huang, Q.J. Chen, C. Deng*, J. Zhang, and Z.Y. Zhong*, Tailor-Making Fluorescent Hyaluronic Acid Microgels via Combining Microfluidics and Photoclick Chemistry for Sustained and Localized Delivery of Herceptin in Tumor, ACS Appl. Mater. Interfaces2018, 10, 3929-3937.
36.M. Qiu, Z.Q. Zhang, Y.H. Wei, H.L. Sun, F.H. Meng, C. Deng*, and Z.Y. Zhong*, Small-sized and robust chimaeric lipopepsomes: A simple and functional platform with high protein loading for targeted intracellular delivery of protein toxin in vivo, Chem. Mater. 2018, 30, 6831-6838.
37.S. Xue, X.L. Gu, J. Zhang, H.L. Sun, C. Deng*, and Z.Y. Zhong*, Construction of small-sized, robust, and reduction-responsive polypeptide micelles for high loading and targeted delivery of chemotherapeutics, Biomacromolecules 2018, 19, 3586-3593.
38.X.L. Gu, M. Qiu, H.L. Sun, J. Zhang, L. Cheng, C. Deng*, and Z.Y. Zhong*,Polytyrosine nanoparticles enable ultra-high loading of doxorubicin and rapidly enzyme-responsive drug release, Biomater.Sci.2018, 6, 1526-1534.
39.T. Chen, M. Qiu, J. Zhang, H.L. Sun, C. Deng*, and Z.Y. Zhong*, Integrated Multifunctional Micelles Co-Self-Assembled from Polypeptides Conjugated with Natural Ferulic Acid and Lipoic Acid for Efficient and Bioresponsive Doxorubicin Delivery, ChemPhysChem2018, 19, 2070-2077.
40.Y.Q. Zhu, Y. Jiang, F.H. Meng, C. Deng, R. Cheng, J. Zhang*, J. Feijen*, and Z.Y. Zhong*, Highly efficacious and specific anti-glioma chemotherapy by smart tandem nanomicelles co-functionalized with brain tumor-targeting and cell-penetrating peptides, J. Control. Release2018,278, 1-8.
41.W.J. Yang, Y.F. Xia, Y. Fang, F.H. Meng*, J. Zhang, R. Cheng, C. Deng, and Z.Y. Zhong*, Selective Cell Penetrating Peptide-Functionalized Polymersomes Mediate Efficient and Targeted Delivery of Methotrexate Disodium to Human Lung Cancer In Vivo, Adv. Healthcare Mater.2018, 1701135.
42.M. Qiu, J. Ouyang, H.L. Sun, F.H. Meng, R. Cheng, J. Zhang, L. Cheng, Q. Lan, C. Deng*, and Z.Y. Zhong*, Biodegradable Micelles Based on Poly(ethylene glycol)-b-Polylipopeptide Copolymer: A Robust and Versatile Nanoplatform for Anticancer Drug Delivery, ACS Appl. Mater. Interfaces2017, 9, 27587-27595.
43.J. Chen, J. Ouyang, Q.J. Chen, C. Deng*, F.H. Meng, J. Zhang, R. Cheng, Q. Lan, and Z.Y. Zhong*, EGFR and CD44 Dual-Targeted Multifunctional Hyaluronic Acid Nanogels Boost Protein Delivery to Ovarian and Breast Cancers In Vitro and In Vivo, ACS Appl. Mater. Interfaces2017, 9, 24140-24147.
44.J.T. Wu, J. Zhang, C. Deng*, F.H. Meng, R. Cheng, and Z.Y. Zhong*, Robust, Responsive and Targeted PLGA Anticancer Nanomedicines by Combining Reductively Cleavable Surfactant and Covalent Hyaluronic Acid Coating, ACS Appl. Mater. Interfaces2017, 9, 3985-3994.
45.J.T. Wu, C. Deng*, F.H. Meng, J. Zhang, H.L. Sun, and Z.Y. Zhong*, Hyaluronic Acid Coated PLGA Nanoparticulate Docetaxel Effectively Targets and Suppresses Orthotopic Human Lung Cancer, J. Control. Release2017, 259, 76-82.
46.Y.N. Zhong, F.H. Meng*, C. Deng, X.L. Mao*, and Z.Y. Zhong*, Targeted Inhibition of Human Hematological Cancers In Vivo by Doxorubicin Encapsulated in Smart Lipoic Acid-Crosslinked Hyaluronic Acid Nanoparticles, Drug Delivery 2017, 24, 1482-1490.
47.Y.Q. Zhu, J. Zhang, F.H. Meng, C. Deng, R. Cheng, J. Feijen*, and Z.Y. Zhong*, cRGD/TAT dual-ligand reversibly crosslinked micelles loaded with docetaxel penetrate deeply into tumor tissue and show high antitumor efficacy in vivo, ACS Appl. Mater. Interfaces2017, 9, 35651-35663.
48.P. Zhong, X.L. Gu, R. Cheng*, C. Deng, F.H. Meng, and Z.Y. Zhong*,αvβ3Integrin-Targeted Micellar Mertansine Prodrug Effectively Inhibits Triple-Negative Breast Cancer In Vivo, Int. J. Nanomed. 2017, 12, 7913-7921.
49.J. Qiu, R. Cheng*, J. Zhang, H.L. Sun, C. Deng, F.H. Meng, and Z.Y. Zhong*, Glutathione-Sensitive Hyaluronic Acid-Mercaptopurine Prodrug Linked via Carbonyl Vinyl Sulfide: A Robust and CD44-Targeted Nanomedicine for Leukemia, Biomacromolecules 2017, 18, 3207-3214.
50.K.Q. Wu, R. Cheng*, J. Zhang, F.H. Meng, C. Deng, and Z.Y. Zhong*,Micellar Nanoformulation of Lipophilized Bortezomib: High Drug Loading, Improved Tolerability and Targeted Treatment of Triple Negative Breast Cancer, J. Mater. Chem. B2017, 5, 5658-5667.
51.P. Zhong, M. Qiu, J. Zhang, H.L. Sun, R. Cheng*, C. Deng, F.H. Meng, and Z.Y. Zhong*, cRGD-Installed Docetaxel-Loaded Mertansine Prodrug Micelles: Redox-Triggered Ratiometric Dual Drug Release and Targeted Synergistic Treatment of B16F10 Melanoma, Nanotechnology 2017, 28, 295103.
52.Y. Fang, Y. Jiang, Y. Zou, F.H. Meng*, J. Zhang, C. Deng, H.L. Sun and Z.Y. Zhong*, Targeted glioma chemotherapy by cyclic RGD peptide-functionalized reversibly core-crosslinked multifunctional poly(ethylene glycol)-b-poly(e-caprolactone) micelles, Acta Biomaterialia 2017, 50, 396-406.
53.Y.Q. Zhu, X.X. Wang, J. Zhang, F.H. Meng, C. Deng, R. Cheng, J. Feijen*, and Z.Y. Zhong*, Exogenous vitamin C boosts the antitumor efficacy of paclitaxel containing reduction-sensitive shell-sheddable micelles in vivo, J. Control. Release2017, 250, 9-19.
54.J. Chen, Y. Zou, C. Deng*, F.H. Meng, J. Zhang, and Z.Y. Zhong*, Multifunctional Click Hyaluronic Acid Nanogels for Targeted Protein Delivery and Effective Cancer Treatment In Vivo, Chem. Mater.2016, 28, 8792-8799.
55.P. Zhong, J. Zhang, C. Deng, R. Cheng*, F.H. Meng, and Z.Y. Zhong*, Glutathione-Sensitive Hyaluronic Acid-SS-Mertansine Prodrug with a High Drug Content: Facile Synthesis and Targeted Breast Tumor Therapy, Biomacromolecules 2016, 17, 3602-3608.
56.Y.N. Zhong, M. Dimde, D. Stöbener, F.H. Meng*, C. Deng, Z.Y. Zhong*, and R. Haag, Micelles with Sheddable Dendritic Polyglycerol Sulfate Shells Show Extraordinary Tumor Targetability and Chemotherapy In Vivo, ACS Appl. Mater. Interfaces2016, 8, 27530-27538.
57.W.J. Yang, Y. Zou, F.H. Meng*, J. Zhang, R. Cheng, C. Deng, and Z.Y. Zhong*, Efficient and targeted suppression of human lung tumor xenografts in mice with methotrexate sodium encapsulated in all-function-in-one chimaeric polymersomes, Adv. Mater.2016, 28, 8234-8239.
58.Y.Q. Zhu, X.X. Wang, J. Chen, J. Zhang, F.H. Meng, C. Deng, R. Cheng, J. Feijen*, and Z.Y. Zhong*, Bioresponsive and fluorescent hyaluronic acid-iodixanol nanogels for targeted X-ray computed tomography imaging and chemotherapy of breast tumors, J. Control. Release2016, 244, 229-239.
59.Y. Zou, F.H. Meng*, C. Deng, and Z.Y. Zhong*, Robust, tumor-homing and redox-sensitive polymersomal doxorubicin: A superior alternative to Doxil and Caelyx? J. Control. Release2016, 239, 149-158.
60.S. Li, J. Zhang, C. Deng*, F.H. Meng, L. Yu, and Z.Y. Zhong*, Redox-Sensitive and Intrinsically Fluorescent Photoclick Hyaluronic Acid Nanogels for Traceable and Targeted Delivery of Cytochrome C to Breast Tumor In Mice, ACS Appl. Mater. Interfaces2016, 8, 21155-21162.
61.B.F. Sun, C. Deng*, F.H. Meng, J. Zhang, and Z.Y. Zhong*, Robust, Active Tumor-Targeting and Fast Bioresponsive Anticancer Nanotherapeutics Based on Natural Endogenous Materials, Acta Biomaterialia 2016, 45, 223-233.
62.J.T. Wu, J. Zhang, C. Deng*, F.H. Meng, and Z.Y. Zhong*, Vitamin E-Oligo(methyl diglycol L-glutamate) as a Biocompatible and Functional Surfactant for Facile Preparation of Active Tumor-Targeting PLGA Nanoparticles, Biomacromolecules 2016, 17, 2367-2374.
63.Y. Zou, H. Meng, F.H. Meng*, C. Deng, J. Zhang, and Z.Y. Zhong*, Self-crosslinkable and intracellularly decrosslinkable biodegradable micellar nanoparticles: a robust, simple and multifunctional nanoplatform for high-efficiency targeted cancer chemotherapy, J. Control. Release2016, 244, 326-335.
64.Y.Q. Zhu, J. Zhang*, F.H. Meng, C. Deng, R. Cheng, J. Feijen*, and Z.Y. Zhong*, cRGD-functionalized reduction-sensitive shell-sheddable biodegradable micelles mediate enhanced doxorubicin delivery to human glioma xenografts in vivo, J. Control. Release2016, 233, 29-38.
65.X.X. Wang, J. Zhang, R. Cheng*, F.H. Meng, C. Deng, and Z.Y. Zhong*, Facile synthesis of reductively degradable biopolymers using cystamine diisocyanate as a coupling agent, Biomacromolecules 2016, 17, 882-890.
66.Y.N. Zhong, K. Goltsche, L. Cheng, F. Xie, F.H. Meng*, C. Deng, Z.Y. Zhong*, and R. Haag, Hyaluronic acid-shelled acid-activatable paclitaxel prodrug micelles effectively target and treat CD44-overexpressing human breast tumor xenografts in vivo, Biomaterials2016, 84, 250-261.
67.X. Li, W.J. Yang, Y. Zou, F.H. Meng*, C. Deng, and Z.Y. Zhong*, Efficacious delivery of protein drugs to prostate cancer cells by PSMA-targeted pH-responsive chimaeric polymersomes, J. Control. Release2015, 220, 704-714.
68.W.T. Lu, X.X. Wang, R. Cheng*, C. Deng, F.H. Meng, and Z.Y. Zhong*, Biocompatible and Bioreducible Micelles Fabricated from Novel α–Amino Acid-Based Poly(Disulfide Urethane)s: Design, Synthesis and Triggered Doxorubicin Release, Polym. Chem. 2015, 6, 6001-6010.
69.W. Chen, F.H. Meng, R. Cheng, C. Deng, J. Feijen*, and Z.Y. Zhong*, Facile Construction of Dual-Bioresponsive Biodegradable Micelles with Superior Extracellular Stability and Activated Intracellular Drug Release, J. Control. Release2015, 210, 125-133.
70.W. Chen, F.H. Meng, R. Cheng, C. Deng, J. Feijen*, and Z.Y. Zhong*, Biodegradable Glycopolymer-b-Poly(ε-caprolactone) Block Copolymer Micelles: Versatile Construction, Tailored Lactose Functionality, and Hepatoma-Targeted Drug Delivery, J. Mater. Chem. B2015, 3, 2308-2317.
71.P.P. Chen, M. Qiu, C. Deng*, F.H. Meng, J. Zhang, R. Cheng, and Z.Y. Zhong*, pH-Responsive Chimaeric Pepsomes Based on Asymmetric Poly(ethylene glycol)-b- Poly(L-leucine)- b-Poly(L-glutamic acid) Triblock copolymer for Efficient Loading and Active Intracellular Delivery of Doxorubicin Hydrochloride, Biomacromolecules2015, 16, 1322-1330.
72.H.L. Sun, R. Cheng, C. Deng, F.H. Meng*, A.A. Dias, M. Hendriks, J. Feijen, and Z.Y. Zhong*, Enzymatically and Reductively Degradable a-Amino Acid-Based Poly(ester amide)s: Synthesis, Cell Compatibility, and Intracellular Anticancer Drug Delivery, Biomacromolecules2015, 16, 597-605.
73.Y.N. Zhong, J. Zhang, R. Cheng*, C. Deng, F.H. Meng, F. Xie*, and Z.Y. Zhong*, Reversibly Crosslinked Hyaluronic Acid Nanoparticles for Active Targeting and Intelligent Delivery of Doxorubicin to Drug Resistant CD44+ Human Breast Tumor Xenografts, J. Control. Release2015, 205, 144-154.
74.G.H. Xu, X.L. Wang, C. Deng*, X.M. Teng, E.J. Suuronen, Z.Y. Shen*, and Z.Y. Zhong*, Injectable Biodegradable Hybrid Hydrogels Based on Thiolated Collagen and Oligo(acryloyl carbonate)-Poly(ethylene glycol)-Oligo(acryloyl carbonate) Copolymer for Functional Cardiac Regeneration, Acta Biomaterialia 2015, 15, 55-64.
75.N.J.R. Blackburn, T. Sofrenovic, D. Kuraitis, A. Ahmadi, B. McNeill, C. Deng, K.J. Rayner, Z.Y. Zhong, M. Ruel, and E.J. Suuronen*, Timing underpins the benefits associated with injectable collagen biomaterial therapy for the treatment of myocardial infarction, Biomaterials2015, 39, 182-192.
76.W. Chen, F.H. Meng, R. Cheng, C. Deng, J. Feijen*, and Z.Y. Zhong*, Advanced Drug and Gene Delivery Systems Based on Functional Biodegradable Polycarbonates and Copolymers, J. Control. Release2014, 190, 398-414.
77.Y.N. Zhong, F.H. Meng, C. Deng*, and Z.Y. Zhong*, Ligand-Directed Active Tumor-Targeting Polymeric Nanoparticles for Cancer Chemotherapy, Biomacromolecules2014, 15, 1955-1969.
78.Y.J. Jiang, J. Chen, C. Deng*, E. Suuronen, and Z.Y. Zhong*, Click Hydrogels, Microgels and Nanogels: Emerging Platforms for Drug Delivery and Tissue Engineering, Biomaterials 2014, 35, 4969-4985.
79.C. Deng, J.T. Wu, R. Cheng, F.H. Meng, H.A. Klok, and Z.Y. Zhong*, Functional Polypeptide and Hybrid Materials: Precision Synthesis via α-Amino Acid N-Carboxyanhydride Polymerization and Emerging Biomedical Applications, Prog. Polym. Sci.2014, 39, 330-364.
80.W. Chen, Y. Zou, F.H. Meng, R. Cheng, C. Deng*, J. Feijen, and Z.Y. Zhong*, Glyco-nanoparticles with sheddable saccharide shells: A unique and potent platform for hepatoma-targeting delivery of an ticancer drugs, Biomacromolecules2014, 15, 900-907.
81.H.L. Sun, F.H. Meng*, R. Cheng, C. Deng, and Z.Y. Zhong*, Reduction and pH dual-bioresponsive crosslinked polymersomes for efficient intracellular delivery of proteins and potent induction of cancer cell apoptosis, Acta Biomaterialia 2014, 10, 2159-2168
82.F.H. Meng, Y.N. Zhong, R. Cheng, C. Deng, and Z.Y. Zhong*, pH-Sensitive polymeric nanoparticles for tumor-targeting doxorubicin delivery: Concept and recent advances, Nanomedicine2014, 9, 487-499. (invited review)
83.H.L. Sun, F.H. Meng*, R. Cheng, C. Deng, and Z.Y. Zhong*, Reduction-Responsive Polymeric Micelles and Vesicles for Triggered Intracellular Drug Release, Antioxidants & Redox Signaling 2014, 21, 755-767. (invited forum article)
84.W.W. Guo, M. Zheng, Y.N. Zhong, F.H. Meng, C. Deng*, and Z.Y. Zhong*, Poly(ethylene oxide)-graft-methotrexate Macromolecular Drugs Conjugating via Aminopteridine Ring Exhibit Potent Anticancer Activity, Chinese Journal of Chemistry2014, 32, 57-65.
