Xue-Qiang Chu, Xiao-Ping Xu^*（徐小平）, and Shun-Jun Ji^*（纪顺俊）

Key Laboratory of Organic Synthesis of Jiangsu Province College of Chemistry, Chemical Engineering and Materials Science Collaborative Innovation Center of Suzhou Nano Science and Technology Soochow University, Suzhou 215123

Chem. Eur. J. 2016, 22, 14181 – 14185

An aqueous catalytic method for double C−S bond formations that involves alcohol derivatives, organic halides, and sodium thiosulfate has been developed. A diverse range of functionalized sulfides, including pharmaceutical and biological derivatives, can be obtained in an efficient and eco-friendly manner under air. The mechanistic studies revealed that this tetrabutylammonium-iodide-catalyzed/water-assisted reaction generated a mercaptan species as the key intermediate.

链接：http://onlinelibrary.wiley.com/doi/10.1002/chem.201603099/abstract