吴新鑫


2020/01- 至今                   苏州大学,材料与化学化工学部,副教授

2016/11-2019/12                苏州大学,材料与化学化工学部,博士后,导师:朱晨教授

2016/07-2016/11                扬子江药业集团江苏海岸药业有限公司,高级研究员

2011/09-2016/07                华东理工大学,博士,制药工程,导师:叶金星教授

2007/09-2011/07                南京工业大学,学士,制药工程

 

 

 

研究领域:   自由基化学,不对称催化,绿色化学,计算化学

 

 

代表性论文:

1. Xinxin Wu, and Chen Zhu*. Radical-Mediated Remote Functional Group Migration. Acc. Chem. Res.2020, 53, 1620-1636.

2. Xinxin Wu†, Mingyang Wang†, Leitao Huan, Dongping Wang, Jinwei Wang, and Chen Zhu*. Tertiary-Alcohol-Directed Functionalization of Remote C(sp3)-H Bonds by Sequential Hydrogen Atom and Heteroaryl Migrations. Angew. Chem. Int. Ed. 2018, 57, 1640-1644. (†co-first author)

3. Xinxin Wu, Hong Zhang, Nana Tang, Zhen Wu, Dongping Wang, Meishan Ji, Yan Xu, Min Wang, Chen Zhu*. Metal-free alcohol-directed regioselective heteroarylation of remote unactivated C(sp3)-H bonds. Nature Communications, 2018, 9, 3343.

4. Shuo Wu†, Xinxin Wu†, Dongping Wang, and Chen Zhu*. Regioselective Vinylation of Remote Unactivated C(sp3)-H Bonds: Access to Complex Fluoroalkylated Alkenes. Angew. Chem. Int. Ed.2019, 58, 1499-1503. (†co-first author)

5. Nana Tang†, Xinxin Wu†, and Chen Zhu*. Practical, Metal-free Remote Heteroarylation of Amides via Unactivated C(sp3)-H Bond Functionalization. Chem. Sci., 2019, 10, 6915-6919. (†co-first author)

6. Xinxin Wu, and Chen Zhu*. Radical Functionalization of Remote C(sp3)-H Bonds Mediated by Unprotected Alcohols and Amides. CCS Chem.2020, 2, 813-828.

7. Xinxin Wu, and Chen Zhu*. Recent Advances in Alkoxy Radical-promoted C-C and C-H Bond Functionalization Starting from Free Alcohols. Chem. Commun.2019, 55, 9747-9756.

8. Xinxin Wu, and Chen Zhu*. Recent Advances in Radical-Mediated C-C Bond Fragmentation of Non-Strained Molecules. Chin. J. Chem.2019, 37, 171-182.

9. Xinxin Wu, and Chen Zhu*. Recent Advances in Ring-Opening Functionalization of Cycloalkanols by C-C s-Bond Cleavage. Chem. Rec.2018, 18, 587-598.

10. Xinxin Wu, Shuo Wu, and Chen Zhu*. Radical-mediated Difunctionalization of Unactivated Alkenes through Distal Migration of Functional Groups. Tetrahedron Lett.2018, 59, 1328-1336.

11. Xinxin Wu, Chunna Meng, Xiaoqian Yuan, Xiaotong Jia, Xuhong Qian, and Jinxing Ye*. Transition-metal-free Visible-light Photoredox Catalysis at Room-temperature for Decarboxylative Fluorination of Aliphatic Carboxylic Acids by Organic Dyes. Chem. Commun.2015, 51, 11864-11867.

12. Min Wang, Huihui Zhang, Jige Liu, Xinxin Wu, and Chen Zhu*. Radical Monofluoroalkylative Alkynylation of Olefins by a Docking-Migration Strategy. Angew. Chem. Int. Ed.2019, 58, 17646-17650.

13. Jige Liu, Shuo Wu, Jiajia Yu, Chenxi Lu, Zhen Wu, Xinxin Wu, Xiao-Song Xue, and Chen Zhu*. Polarity Umpolung Strategy for the Radical Alkylation of Alkenes. Angew. Chem. Int. Ed.2020, 59, 8195-8202.

14. Mingyang Wang, Man Li, Shan Yang, Xiao-Song Xue*, Xinxin Wu, and Chen Zhu*. Radical-mediated C-C Cleavage of Unstrained Cycloketones and DFT Study for Unusual Regioselectivity. Nature Communications, 2020, 11, 672.

15. Huihui Zhang, Luyao Kou, Dong Chen, Meishan Ji, Xiaoguang Bao,* Xinxin Wu, and Chen Zhu*. Radical-Mediated Distal Ipso-Migration of O/S-Containing Heteroaryls and DFT Studies for Migratory Aptitude. Org. Lett.2020, 22, 5947-5952.