孙欢利
姓名:孙欢利
职称:副教授

部门:材料学院
联系方式:

Tel/fax86-512-65884910 

Emailsunhuanli@suda.edu.cn


课题组网站
学历及学术经历:

19871月生于河南省汝州市,博士,苏州大学副教授,美国化学会期刊《生物大分子》副主编助理,生物医用高分子实验室成员。20086月于苏州大学化学工程与工艺专业获工学学士学位,20136月于苏州大学高分子化学与物理专业获理学博士学位(导师:钟志远教授)。20111-20112月在荷兰帝斯曼公司培训学习。2013-2015年于澳大利亚墨尔本大学化学与分子生物学院从事博士后研究。20159月受聘为苏州大学副教授。

博士期间曾获得苏州大学优秀博士论文选题立项重点资助以及江苏省普通高校研究生科研创新计划项目资助。在国际主流期刊如Chemical ScienceBiomaterialsJournal of Controlled ReleaseBiomacromolecules等上发表近20篇学术论文。

 

研究领域:多功能性纳米药物载体,肿瘤的靶向治疗

 

代表性论文:

1. H.L. Sun, E.H.H. Wong, Y. Yan, J.W. Cui, Q. Dai, J.L. Guo, G.G. Qiao, F. Caruso, The Role of Capsule Stiffness on Cellular Processing. Chemical Science, 2015, 6, 3505-3514.

2. H.L. Sun, M. Björnmalm, J.W. Cui, E.H.H. Wong, Y.L. Dai, Q. Dai, G.G. Qiao, F. Caruso, Structure Governs the Deformability of Polymer Particles in a Microfluidic Blood Capillary Model. ACS Macro Letters 2015, 4, 1205-1209

3. H.L. Sun, R. Cheng, C. Deng, F.H. Meng, A.A. Dias, M. Hendriks, J. Feijen, Z.Y. Zhong, Enzymatically and Reductively Degradable α-Amino Acid-Based Poly(ester amide)s: Synthesis, Cell Compatibility, and Intracellular Anticancer Drug Delivery. Biomacromolecules 2015, 16, 597-605.

4. H.L. Sun, F.H. Meng, R. Cheng, C. Deng, Z.Y. Zhong, Reduction-Responsive Polymeric Micelles and Vesicles for Triggered Intracellular Drug Release. Antioxidant and Redox Signaling 2014, 21, 755-767.

5. H.L. Sun, F.H. Meng, R. Cheng, C. Deng, Z.Y. Zhong, Reduction and pH Dual-Bioresponsive Crosslinked Polymersomes for Efficient Intracellular Delivery of Proteins and Potent Induction of Cancer Cell Apoptosis. Acta Biomaterialia 2014, 10, 2159-2168.

6. H.L. Sun, F.H. Meng, R. Cheng, C. Deng, Z.Y. Zhong, Reduction-Sensitive Degradable Mi-cellar Nanoparticles as Smart and Intuitive Delivery Systems for Cancer Chemotherapy. Ex-pert Opinion on Drug Delivery 2013, 10, 1109-1122.

7. H.L. Sun, F.H. Meng, R. Cheng, C. Deng, Z.Y. Zhong. Reversibly Crosslinked pH Sensitive Polymersomes for Efficient Intracellular Protein Delivery. Journal of Controlled Release 2013, 172, e104.

8. W. Wang, H.L. Sun (co-first author), F.H. Meng, S.B. Ma, H.Y. Liu, Z.Y. Zhong, Precise Control of Intracellular Drug Release and Anti-Tumor Activity of Biodegradable Micellar Drugs via Reduction-Sensitive Shell-Shedding. Soft Matter 2012, 8, 3949-3956.

9. H.L. Sun, F.H. Meng, A.A. Dias, M. Hendriks, J. Feijen, Z.Y. Zhong, α-Amino Acid Containing Degradable Polymers as Functional Biomaterials: Rational Design, Synthetic Pathway, and Biomedical Applications. Biomacromolecules 2011, 12, 1937-1955.

10. H.L. Sun, B.N. Guo, R. Cheng, F.H. Meng, H.Y. Liu, Z.Y. Zhong, Reduction-Responsive Shell-Sheddable Biodegradable Micelles for Intracellular Doxorubicin Delivery. Journal of Controlled Release 2011, 152, e84-85.

11.H.L. Sun, B.N. Guo, X.Q. Li, R. Cheng, F.H. Meng, H.Y. Liu, Z.Y. Zhong, Shell-Sheddable Mi-celles based on Dextran-SS-Poly(ε-caprolactone) Diblock Copolymer for Efficient Intracellular Release of Doxorubicin. Biomacromolecules 2010, 11, 848-854.

12.H.L. Sun, B.N. Guo, R. Cheng, F.H. Meng, H.Y. Liu, Z.Y. Zhong, Biodegradable Micelles with Sheddable Poly(ethylene glycol) Shells for Triggered Intracellular Release of Doxorubicin. Biomaterials 2009, 30, 6358-6366.