学历及学术经历:

1983年7月徐州师范大学本科毕业，1990年7月获南京大学有机化学专业硕士学位，2004年6月获南京大学有机化学专业博士学位。1983年8月至2008年5月在徐州师范大学化学系（现江苏师范大学化学化工学院）工作，2000年8月任教授，曾任徐州师范大学化学系主任。2008年6月起在苏州大学材料与化学化工学部工作，任教授、博士生导师。2011年起任SCI源期刊Journal of Heterocyclic Chemistry 杂志编委。先后应邀为Chem. Rev., J. Org. Chem., Org. Lett., Green Chem., ACS Comb. Sci., ACS Sustain Chem. Eng., Tetrahedron等40余种国际化学专业期刊审稿人。先后主持了十多项国家、省、厅级基金项目。在包括 Chem. Sci., Chem. Commun., Org. Lett., J. Org. Chem., Green Chem., Adv. Synth. Catal., RSC Adv., ACS Comb. Sci., J. Comb. Chem., Org. Biomol. Chem., Eur. J. Org. Chem., Tetrahedron, Tetrahedron Lett., Synlett, Synthesis等国内外核心期刊上发表高质量论文290余篇。2004年获江苏省高校优秀教学成果一等奖（排名第2），指导的硕士论文有2篇被评为江苏省优秀硕士论文。先后被评为江苏省优秀青年骨干教师（1996年）、江苏省“333工程”第三层次培养人选（1997年和2001年）、江苏省“青蓝工程”跨世纪学术带头人培养人选（1998年）、江苏省优秀教育工作者（2001年）、江苏省“333高层次人才培养工程”首批中青年科学技术带头人（2007年）。成果“功能性杂环有机分子的合成、性质及应用研究”2013年获教育部高等学校科学研究优秀成果奖(科学技术)奖自然科学奖二等奖（排名第2），成果“杂环化合物的定向合成及活性研究” 2011 年获中国石油和化学工业联合会科技进步二等奖（排名第1）。

研究方向:

有机合成方法学研究：包括多组分反应；杂环化合物的设计、合成及性质研究；碳氢键活化反应；杂螺烯类似物的合成等

近五年发表论文代表作：

1. Highly selective synthesis of functionalized polyhydroisoquinoline derivatives via a three-component domino reaction. X. Feng, J. J. Wang, Z. Xun, J. J. Zhang, Z. B. Huang, D. Q. Shi*, Chem. Commun., 2015, 51, 1528.

2. Multicomponent strategy to indeno[2,1-c]pyridine and hydroisoquinoline derivatives through cleavage of carbon-carbon bond. X. Feng, J. J. Wang, Z. Xun, Z. B. Huang, D. Q. Shi*, J. Org. Chem., 2015, 80, 1025.

3. Regioselective synthesis of functionalized [1,8]naphthyridine derivatives via a three-component domino reaction under catalyst-free conditions. X. Feng, J. J. Wang, J. J. Zhang, C. P. Cao, Z. B. Huang; D. Q. Shi*, Green Chem., 2015, 17, 973.

4. Highly efficient construction of a bridged pentacyclic skeleton via a six-component domino reaction under microwave irradiation. L. Fu, X. Feng, J. J. Zhang, J. D. Hu, Z. Xun, J. J. Wang, Z. B. Huang, D. Q. Shi*, Green Chem., 2015, 17, 1535.

5. Efficient Synthesis and Evaluation of Antitumor Activities of Novel Functionalized 1,8-Naphthyridines Derivatives. L. Fu, X. Feng, J. J. Wang, Z. Xun, J. D. Hu, J. J. Zhang, Y. W. Zhao, Z. B. Huang, D. Q. Shi*, ACS Comb. Sci., 2015, 17, 24.

6. Highly site-selective sequential alkenylation of oxalyl amide protected phenylpropylamine derivatives via a seven-membered palladacycle. Q. Wang, J. Han, C. Wang, J. Y. Zhang, Z. B. Huang, D. Q. Shi*, Y. S. Zhao*, Chem. Sci., 2014, 5, 4962.

7. Selective synthesis of polyfunctionalized pyrido[2,3-b]indoles by multicomponent domino reactions. J. D. Hu, C. P. Cao, W. Lin, M. H. Hu, Z. B. Huang*, D. Q. Shi*, J. Org. Chem., 2014, 79, 7935.

8. Oxalyl Amide Assisted Palladium-Catalyzed Arylation of C(sp²)-H Bond at the δ Position. J. Han, P. Liu, C. Wang, Q. Wang, J. Y. Zhang, Y. W. Zhao, D. Q. Shi, Z. B. Huang*, Y. S. Zhao*, Org. Lett., 2014, 16, 5682.

9. Fe-promoted oxidative cyclization of α-benzoylthioformanilides for the synthesis of 2-benzoyl- benzothiazoles. X. Feng, Q. Wang, Z. B. Huang, D. Q. Shi*, RSC Adv., 2014, 4, 54719.

10. Selective synthesis of polyfunctionalized hydroisoquinoline derivatives via a three-component domnio reaction. J. J. Zhang, J. D. Hu, C. P. Cao, G. L. Dou, L. Fu, Z. B. Huang, D. Q. Shi*, RSC Adv., 2014, 4, 62457.

11. Efficient Synthesis of Functionalized Benzo[b][1,8]naphthyridine Derivatives via Three-Component Reaction Catalyzed by L-Proline. L. Fu, W. Lin, M. H. Hu, X. C. Liu, Z. B. Huang*, D. Q. Shi*, ACS Comb. Sci., 2014, 16, 238.

12. Efficient and Regioselective Synthesis of Novel Functionalized Dispiropyrrolidines and Their Cytotoxic Activities. J. M. Yang, Y. Hu, Q. Li, F. Yu, J. Cao, D. Fang, Z. B. Huang, D. Q. Shi*, ACS Comb. Sci., 2014, 16, 139.

13. Selective reduction of carbonyl groups in the presence of low-valent titanium reagents. W. Lin, M. H. Hu, X. Feng, L. Fu, C. P. Cao, Z. B. Huang*, D. Q. Shi*, Tetrahedron Lett., 2014, 55, 2238.

14. An efficient three-component synthesis of highly functionalized tetrahydroacenaphtho[1,2-b]indolone derivatives catalyzed by L-proline. J. J. Zhang, X. Feng, X. C. Liu, Z. B. Huang, D. Q. Shi*, Mol. Divers., 2014, 18, 727.

15. Highly efficient construction of pentacyclic benzo[b]indeno[1,2,3-de][1,8]naphthyridine derivatives via four-component domino reaction. C. P. Cao, W. Lin, M. H. Hu, Z. B. Huang*, D. Q. Shi*, Chem. Commun., 2013, 49, 6983.

16. Highly efficient synthesis of polysubstituted pyrroles via four-component domino reaction. X. Feng, Q. Wang, W. Lin, G. L. Dou, Z. B. Huang*, D. Q. Shi*, Org. Lett., 2013, 15, 2542.

17. Facile, Efficient, and Diastereoselective Synthesis of Heterohelicene-like molecules. W. Lin, G. L. Dou, M. H. Hu, C. P. Cao, Z. B. Huang*, D. Q. Shi*, Org. Lett., 2013, 15, 1238.

18. GAP chemistry for pyrrolyl coumarin derivatives: a highly efficient one-pot synthesis under catalyst-free conditions. H. Y. Wang, X. C. Liu, X. Feng, Z. B. Huang*, D. Q. Shi*, Green Chem., 2013, 15, 3307.

19. Efficient Synthesis of Functionalized Dihydro-1H-indol-4(5H)-ones via One-Pot Three-Component Reaction Under Catalyst-Free Conditions. H. Y. Wang, D. Q. Shi*, ACS Comb. Sci., 2013, 15, 261.

20. An efficient and convenient synthesis of heterocycle-fused indazoles via the N-N bond forming reaction of nitroarenes induced by low-valent titanium reagent. W. Lin, M. H. Hu, X. Feng, C. P. Cao, Z. B. Huang*, D. Q. Shi*, Tetrahedron, 2013, 69, 6721.

21. An Efficient Synthesis of Pyrrolo[2,3,4-kl]acridin-1-one Derivatives Catalyzed by L-Proline. H. Y. Wang, L. L.Li, W. Lin, P. Xu, Z. B. Huang*, D. Q. Shi*, Org. Lett., 2012, 14, 4598.

22. Rapid and Efficient Ultrasound-Assisted Method for the Combinatorial Synthesis of Spiro[indoline-3,4”-pyrano[2,3-c] pyrazole] Derivatives. Y. Zou, Y. Hu, H. Liu, D. Q. Shi*, ACS Comb. Sci., 2012, 14, 38.

23. Novel and efficient synthesis of substituted quinoline-1-oxides and the complex compounds SnL₂Cl₂ (L = 2-aminoquinoline- 1-oxides) with the aid of stannous chloride. L. Fu, W. Lin, P. Xu, Y. K. Xi, M. M. Wang, D. Q. Shi*, Tetrahedron, 2012, 68, 7782.

24. A stereoselective synthesis of symmetrical and unsymmetrical bibenzo[e][1,3]oxazine-2,2’-dione derivatives induced by low- valent titanium reagent. G. L. Dou, F. Sun, D. Q. Shi*, Tetrahedron, 2012, 68, 4852.

25. An efficient synthesis of 2H-indazoles via reductive cyclization of 2-nitrobenzylamines induced by low-valent titanium reagent. F. Sun, X. Feng, X. Zhao, Z. B. Huang, D. Q. Shi*, Tetrahedron, 2012, 68, 3851.

26. A facile and efficient ultrasound-assisted synthesis of novel dispiroheterocycles through 1,3-dipolar cycloaddition reactions. Y. Hu, Y. Zou, H. Wu, D. Q. Shi*, Ultrason. Sonochem., 2012, 19, 264.

27. Efficient One-pot Three-Component Synthesis of Fused Pyridine Derivatives in Ionic Liquid. Z. B. Huang, Y. Hu, Y. Zhou, D. Q. Shi*, ACS Comb. Sci., 2011, 13, 45.

28. A novel and environment-friendly method for preparing dihydropyrano[2,3-c]pyrazoles in water under ultrasound irradiation. Y. Zhou, H. Wu, Y. Hu, H. Liu, X. Zhao, H. L. Ji, D. Q. Shi*, Ultrason. Sonochem., 2011, 18, 708.

29. An Efficient Synthesis of Pyrrolo[1,2-a]quinazolin-5(1H)-one Derivatives with the aid of Low-valent Titanium Reagent. G. L. Dou, D. Q. Shi*, Org. Biomol. Chem., 2011, 9, 7065.

30. Efficient one-pot synthesis of spiro[indoline-3,4'-pyrazolo [3,4-e][1,4]thiazepine]dione via three-component reaction. H. Chen, D. Q. Shi*, Tetrahedron, 2011, 67, 5686.

31. Efficient and convenient synthesis of spiroindoline- quinazolines induced by stannous chloride. Y. Hu, M. M. Wang, H. Chen, D. Q. Shi, Tetrahedron, 2011, 67, 9342.

32. An efficient one-step synthesis of 2-arylquinolin-4(3H)-ones with the aid of low-valent titanium reagent. F. Sun, X. Zhao, D. Q. Shi*, Tetrahedron Lett., 2011, 52, 5633.

33. A novel and convenient synthesis of 4-hydroxy-6-methyl-3-(1- (phenylimino)ethyl)-2H-pyran-2-one derivatives under ultrasound irradiation. H. Y. wang, Y. Zou, X. Zhao, D. Q. Shi*, Ultrason. Sonochem., 2011, 18, 1048.

34. Efficient synthesis of naphtho[1,2-e][1,3]oxazine derivatives via a chemoselective reaction with the aid of low-valent titanium reagent, D. Q. Shi*, S. F. Rong, G. L. Dou, M. M. Wang. J. Comb. Chem., 2010, 12, 25.

35. Oriented synthesis and in vitro anticancer activity of biquinazoline-2,2’-diones. G. L. Dou, D. Q. Shi*, Y. H. Li, J. Comb. Chem., 2010, 12, 195.

36. Efficient one-pot synthesis of spirooxindole derivatives catalyzed by L-proline in aqueous medium. Y. L. Li, H. Chen, C. L. Shi, D. Q. Shi*, S. J. Ji, J. Comb. Chem., 2010, 12, 231.

37. Regio- and stereoselective synthesis of novel dispiropyrrolidine bisoxindole derivatives via multicomponent reactions. H. Liu, G. L. Dou, D. Q. Shi*, J. Comb. Chem., 2010, 12, 292.

38. Regioselective Synthesis and in Vitro Anticancer Activity of 4-Aza-podophyllotoxin Derivatives Catalyzed by L-Proline. C. L. Shi, J. X. Wang, H. Chen, D. Q. Shi*, J. Comb. Chem., 2010, 12, 430.

39. Efficient One-Pot Synthesis of Novel Spirooxindole Derivatives via Three-Component Reaction in Aqueous Medium. H. Chen, D. Q. Shi*, J. Comb. Chem., 2010, 12, 571.

40. Efficient and Convenient Synthesis of Pyrrolo[1,2-a] quinazoline Derivatives with the Aid of Tin (II) Chloride. M. M. Wang, G. L. Dou, D. Q. Shi*, J. Comb. Chem., 2010, 12, 582.

41. Regioselective Synthesis of Novel Spiropyrrolidines and Spirothiapyrrolizidines Through Mnlticomponent 1,3-Dipolar Cycloaddition Reaction of Azomethin Ylides. H. Liu, G. L. Dou, D. Q. Shi*, J. Comb. Chem., 2010, 12, 633.