钟志远
  姓名:钟志远
  职称:教授、博士生导师

  部门:材料学院
  联系方式:
Tel/fax: 86-512-65880098
Email: zyzhong@suda.edu.cn
课题组网站:http://bmp.suda.edu.cn

 课题组网站

学历及学术经历:
19742月生于江西省安远县,苏州大学特聘教授,国家杰出青年基金获得者(2012),江苏特聘教授(2013),德国亥姆霍兹国家究中心生物材料研究所客座教授2013,柏林自由大学客座教授(2013)。苏州大学生物医用高分子材料重点实验室主任,江苏省先进功能高分子材料设计及应用重点实验室副主任。2002年荷兰屯特大学获博士学位。2002-2007年荷兰屯特大学任助理教授。2011-2012年担任苏州工业园区生物产业发展有限公司(苏州生物纳米园)副总裁。担任J. Controlled Release (1)Journal of Materials Chemistry B (1)Biomacromolecules 2区),J. Biomater. Sci., Polym. Ed. (2)等国际著名期刊编委,《中国科学:化学》青年工作委员会成员(Promotion Editor),J. Controlled Release (1)客座主编,第一、第二和第三届新型高分子材料与控制释放国际会议(SIPCD 201020122014)执行组委会主席,国家自然科学基金委员会专家评审组专家等学术兼职。在国际主流期刊发表论文110多篇,2篇论文入选“中国百篇最具影响国际学术论文”,论文共被引用5300多次,H-因子41。应邀在国际学术会议上做邀请报告40多次。现主持3项国家自然科学基金项目和2项国际公司合作项目。获得的荣誉奖励包括:美国化学会期刊部和高分子分会颁发的“生物大分子/大分子青年研究者奖”(2014)、德国洪堡基金会“贝塞尔研究奖”(2013)、日本药物释放系统学会的“亚洲药物释放系统突破技术奖”(2013)、江苏特聘教授(2013)、江苏省333工程第二层次培养对象(2013)、苏州市十佳魅力科技人物(2013)、国家杰出青年科学基金获得者(2012等。

 

研究领域: 生物医用高分子材料、药物控制释放、基因释放、生物组织工程、肿瘤靶向治疗。

 

代表性论文

 

1.      Y.J. Jiang, J. Chen, C. Deng*, E. Suuronen, and Z.Y. Zhong*, Click Hydrogels, Microgels and Nanogels: Emerging Platforms for Drug Delivery and Tissue Engineering, Biomaterials 2014, http://dx.doi.org/10.1016/j.biomaterials.2014.03.001.

2.      C. Deng, J.T. Wu, R. Cheng, F.H. Meng, H.A. Klok, and Z.Y. Zhong*, Functional Polypeptide and Hybrid Materials: Precision Synthesis via α-Amino Acid N-Carboxyanhydride Polymerization and Emerging Biomedical Applications, Prog. Polym. Sci.2014, 39,330-364.

3.      W. Chen, Y. Zou, F.H. Meng, R. Cheng, C. Deng, J. Feijen, and Z.Y. Zhong*, Glyco-Nanoparticles with Sheddable Saccharide Shells: A Unique and Potent Platform for Hepatoma-Targeting Delivery of Anticancer Drugs, Biomacromolecules2014,15, 900-907.

4.      Y.N. Zhong, W.J. Yang, H.L. Sun, R. Cheng, F.H. Meng, C. Deng*, and Z.Y. Zhong*, Ligand-Directed Reduction-Sensitive Shell-Sheddable Biodegradable Micelles Actively Deliver Doxorubicin into the Nuclei of Target Cancer Cells, Biomacromolecules2013, 14, 3723-3730.

5.      J.R. Zhou, P.P. Chen, C. Deng*, F.H. Meng, R. Cheng, and Z.Y. Zhong*,A Simple and Versatile Synthetic Strategy to Functional Polypeptides via Vinyl Sulfone-Substituted L-Cysteine N-Carboxyanhydride, Macromolecules2013,46, 6723–6730.

6.      Y.P. Fan, C. Deng*, R. Cheng, F.H. Meng, and Z.Y. Zhong*, In Situ Forming Hydrogels via Catalyst-Free and Bioorthogonal “Tetrazole–Alkene” Photo-Click Chemistry, Biomacromolecules2013, 14, 2814-2821.

7.      X.Y. Wang, H.L. Sun, F.H. Meng*, R. Cheng, C. Deng, and Z.Y. Zhong*, Galactose-Decorated Reduction-Sensitive Degradable Chimaeric Polymersomes as a Multifunctional Nanocarrier To Efficiently Chaperone Apoptotic Proteins into Hepatoma Cells, Biomacromolecules2013, 14, 2873-2882.

8.      Y.D. Gu, Y.N. Zhong, F.H. Meng*, R. Cheng, C. Deng, and Z.Y. Zhong*, Acetal-Linked Paclitaxel Prodrug Micellar Nanoparticles as a Versatile and Potent Platform for Cancer Therapy, Biomacromolecules2013, 14, 2772-2780.

9.      Y.N. Zhong, W. Wang, L. Cheng,  F.H. Meng, Z.Y. Zhong*, and Z. Liu*, Gold Nanorod-Cored Biodegradable Micelles as a Robust and Remotely Controllable Doxorubicin Release System for Potent Inhibition of Drug-Sensitive and -Resistant Cancer Cells, Biomacromolecules2013, 14, 2411-2419.

10.    L.L. Wu, Y. Zou, C. Deng*, R. Cheng, F.H. Meng, and Z.Y. Zhong*, Intracellular Release of Doxorubicin from Core-Crosslinked Polypeptide Micelles Triggered by Both pH and Reduction Conditions, Biomaterials2013, 34, 5262-5272.

11.    W. Chen, M. Zheng, F.H. Meng, R. Cheng, C. Deng, J. Feijen, and Z.Y. Zhong*, In Situ Forming Reduction-Sensitive Degradable Nanogels for Facile Loading and Triggered Intracellular Release of Proteins, Biomacromolecules2013,14, 1214-1222.

12.    H.L. Sun, F.H. Meng*, R. Cheng, C. Deng, and Z.Y. Zhong*, Reduction-Sensitive Degradable Micellar Nanoparticles as Smart and Intuitive Delivery Systems for Cancer Chemotherapy, Expert Opin. Drug Deliv. 2013, 10, 1109-1122.

13.    R. Cheng, F.H. Meng, C. Deng, H.A. Klok, and Z.Y. Zhong*, Dual and Multi-Stimuli Responsive Polymeric Nanoparticles for Programmed Site-Specific Drug Delivery, Biomaterials2013, 34, 3647-3657.

14.    W. Chen, P. Zhong, F.H. Meng*, R. Cheng, C. Deng, J. Feijen, and Z.Y. Zhong*, Redox and pH-Responsive Degradable Micelles for Dually Activated Intracellular Anticancer Drug Release, J. Control. Release2013, 169, 171-179.

15.    W. Chen, Y. Zou, J.N. Jia, F.H. Meng, R. Cheng, C. Deng, J. Feijen, and Z.Y. Zhong*, Functional Poly(ε-caprolactone)s via Copolymerization of εCaprolactone and Pyridyl Disulfide-Containing Cyclic Carbonate: Controlled Synthesis and Facile Access to Reduction-Sensitive Biodegradable Graft Copolymer Micelles, Macromolecules2013, 46, 699-707.

16.    F.H. Meng, R. Cheng, C. Deng, and Z.Y. Zhong*, Intracellular Drug Release Nanosystems, Materials Today 2012, 15, 436-442 (invited review)

17.    Y.L. Wu, W. Chen, F.H. Meng, Z.J. Wang, R. Cheng, C. Deng, H.Y. Liu, and Z.Y. Zhong*, Core-Crosslinked pH-Sensitive Degradable Micelles: A Promising Approach to Resolve the Extracellular Stability Versus Intracellular Drug Release Dilemma, J. Control. Release2012, 164, 338-345.

18.    C. Deng, Y.J. Jiang, R. Cheng, F.H. Meng, and Z.Y. Zhong*, Biodegradable Polymeric Micelles for Targeted and Controlled Anticancer Drug Delivery: Promises, Progress and Prospects, Nano Today 2012, 7, 467-480 (invited review)

19.    R.R. Wei, L. Cheng, M. Zheng, R. Cheng, F.H. Meng, C. Deng, and Z.Y. Zhong*, Reduction-Responsive Disassemblable Core-Cross-Linked Micelles Based on Poly(ethylene glycol)-b-poly(N-2-hydroxypropyl methacrylamide)–Lipoic Acid Conjugates for Triggered Intracellular Anticancer Drug Release, Biomacromolecules2012, 13, 2429-2438.

20.    Y.F. Du, W. Chen, M. Zheng, F.H. Meng, and Z.Y. Zhong*, pH-Sensitive Degradable Chimaeric Polymersomes for the Intracellular Release of Doxorubicin Hydrochloride, Biomaterials2012, 33, 7291-7299.