Name:Jinlin He
  Title:Associate Professor
Tel: +86-512-65882046 (O)

Group Website






Ph.D. (2006.09-2012.06)

Exchange Ph.D. Student, College of Polymer Science and Polymer Engineering, The University of Akron, Ohio, U. S. A.

Major: High-vacuum Living Anionic Polymerization

Mentor: Prof. Stephen Z. D. Cheng

College of Chemistry, Chemical Engineering and Materials Science, Soochow University, P. R. China.

Major: Macromolecular Chemistry and Physics

Mentor: Prof. Peihong Ni

B. Sc. (2002.09-2006.06)

College of Chemistry and Chemical Engineering, Soochow University, P. R. China.

Research Interests:

(1)      Functional polymers synthesis via combination of various polymer synthesis methodologies and highly-efficient organic reactions, including high vacuum living anionic polymerization, oxyanion-initiated polymerization (OIP), controlled/“living” radical polymerization (CLRP), ring-opening polymerization, copper catalyzed azide-alkyne cycloadditions (CuAAC) and thiol-ene “Click” chemistry, and hydrosilylation.

(2)      Stimuli-responsive polymeric micelles and hydrogels.



(1)      Innovation Project of Graduate Students of Jiangsu Province (2009, No. CX09B_021Z).

(2)      “Excellent Poster Award” in International Symposium on Polymer Chemistry (PC2010), June 2-6, 2010, Suzhou, China.

(3)      “Excellent Paper Award” in 2010 Academic Forum for PhD students of Jiangsu Province, March 30-31, 2010, Yangzhou, China.


Research Fundings:

(1)    National Natural Science Foundation China (21304061), 2014.01-2016.12.

(2)    Natural Science Foundation of Jiangsu Province for Young Scholars, 2013.07-2016.06.

(3)    Natural Science Foundation of Jiangsu Higher Education Institutions (13KJB150034), 2013.08-2015.12.

(4)    China Postdoctoral Science Foundation (2013M531396), 2012.09-2014.09.

(5)    Innovation Project of Graduate Students of Jiangsu Province (CX09B_021Z), 2009.08-2012.06.


Recent publications:

(1)Xiao-Man Wang, Yu Shao, Jun Xu, Xin Jin, Rui-Hao Shen, Peng-Fei Jin, Dong-Wei Shen, Jing Wang, Weihua Li, Jinlin He*, Peihong Ni and Wen-Bin Zhang*. “Precision synthesis and distinct assembly of double-chain giant surfactant regio-isomers”, Macromolecules, 2017, 50, 3943-3953. (Equal contribution)

(2)徐俊, 钱强雨,何金林*, 张明祖, 戴礼兴, 倪沛红. “负离子聚合制备环氧化八臂星形聚异戊二烯及其表征”, 高分子学报, 2017, doi: 10.11777/j.issn1000-3304.2017.17087.

(3)晏雪生,徐俊,何金林*, 张明祖, 戴礼兴, 倪沛红. “活性负离子聚合法制备POSS基七臂星形聚合物及其表征”, 高分子学报, 2017, 3, 454-463. (共同第一作者)

(4)Xueqiong Du, Yue Sun, Mingzu Zhang, Jinlin He and Peihong Ni*. “Polyphosphoester-camptothecin prodrug with reduction-response prepared via Michael addition polymerization and click reaction”, ACS Appl. Mater. Interfaces, 2017, 9, 13939-13949.

(5)Yue Sun, Xueqiong Du, Jinlin He, Jian Hu, Mingzu Zhang and Peihong Ni*. “Dual-responsive core-crosslinked polyphosphoester-based nanoparticles for pH/redox-triggered anticancer drug delivery”, J. Mater. Chem. B, 2017, doi: 10.1039/C7TB00440K.

(6)Zixu Gu, Jun Cheng, Mingzu Zhang, Jinlin He and Peihong Ni*. “Effect of sequence structure on wetting behaviors of fluorinated methacrylate polymers based on perfluorohexylethyl methacrylate and stearyl acrylate”, Chinese J. Polym. Sci., 2017, doi: 10.1007/s10118-016-1832-y.

(7)Zixu Gu, Jun Cheng, Mingzu Zhang, Jinlin He and Peihong Ni*. “Effect of groups at α-position and side-chain structure of comonomers on surface free energy and surface reorganization of fluorinated methacrylate copolymer”, Polymer, 2017, 114, 79-87.

(8)Yu Shao, Hang Yin, Xiao-Man Wang, Shuai-Yuan Han, Xuesheng Yan, Jun Xu, Jinlin He*, Peihong Ni and Wen-Bin Zhang*. “Mixed [2:6] hetero-arm star polymers based on Janus POSS with precisely defined arm distribution”, Polym. Chem., 2016, 7, 2381-2388.

(9)Kan Yue, Mingjun Huang, Ryan Marson,Jinlin He, Jiahao Huang, Zhe Zhou, Jing Wang, Chang Liu, Xuesheng Yan, Kan Wu, Zaihong Guo, Hao Liu, Wei Zhang, Peihong Ni, Chrys Wesdemiotis, Wen-Bin Zhang,* Sharon C. Glotzer* and Stephen Z. D. Cheng*. “Geometry induced sequence of nanoscale Frank-Kasper and quasicrystal mesophases in giant surfactants”, Proc. Natl. Acad. Sci. USA, 2016, 113, 14195-14200. (Equal contribution)

(10)Jian Tian, Jie Chen, Cuicui Ge, Xu Liu, Jinlin He*, Peihong Ni and Yue Pan*. “Synthesis of PEGylated ferrocene nanoconjugates as the radiosensitizer of cancer cells”, Bioconjugate Chem., 2016, 27, 1518-1524. (Equal contribution)

(11)Sen Li, Jinlin He*, Mingzu Zhang, Hairong Wang and Peihong Ni*. “Multicompartment morphologies self-assembled from fluorinated ABC triblock terpolymers: Effects of flexible and rigid hydrophobic moieties”, Polym. Chem., 2016, 7, 1773-1781.

(12)Dongling Cao, Jinlin He, Jiaying Xu, Mingzu Zhang, Lin Zhao, Guangxin Duan, Youwen Cao, Ruhong Zhou* and Peihong Ni*. “Polymeric prodrugs conjugated with reduction-sensitive dextran-camptothecin and pH-responsive dextran-doxorubicin: An effective combinatorial drug delivery platform for cancer therapy”, Polym. Chem., 2016, 7, 4198-4212.

(13)Zixu Gu, Mingzu Zhang, Jinlin He and Peihong Ni*. “Surface energy and surface reorganization of perfluorohexylethyl methacrylate/n-alkyl(meth)acrylate copolymers”, Colloids Surf. A: Physicochem. Eng. Asp.,2016, 502, 159-167.

(14)Jian Hu, Mingzu Zhang, Jinlin He and Peihong Ni*. “Injectable hydrogels by inclusion complexation between three-armed star copolymer (mPEG-acetal-PCL-acetal-)3 and α-cyclodextrin for pH-triggered drug delivery”, RSC Adv., 2016, 6, 40858-40868.

(15)Qingqing Zhang, Jinlin He*, Mingzu Zhang and Peihong Ni*. “Polyphosphoester-conjugated camptothecin prodrug with disulfide linkage for potent reduction-triggered drug delivery”, J. Mater. Chem. B, 2015, 3, 4922-4932.

(16)Fei Li, Jinlin He*, Mingzu Zhang, Kam Chiu Tam, Peihong Ni*. “A pH-sensitive and biodegradable supramolecular hydrogel constructed from PEGylated polyphosphoester-doxorubicin prodrug and a-cyclodextrin”, Polym. Chem., 2015, 6, 5009-5014.

(17)Fei Li, Jinlin He, Mingzu Zhang, Kam Chiu Tam, Peihong Ni*, “Injectable supramolecular hydrogels fabricated from PEGylated doxorubicin prodrug and a-cyclodextrin for pH-triggered drug delivery”, RSC Adv., 2015, 5, 54658-54666.

(18)Jian Hu, Jinlin He, Dongling Cao, Mingzu Zhang, Peihong Ni*, “Core cross-linked polyphosphoester micelles with folate-targeted and acid-cleavable features for pH-triggered drug delivery”, Polym. Chem., 2015, 6, 3205-3216. (封面文章)

(19)Jian Hu, Jinlin He*, Mingzu Zhang, Peihong Ni*. “Precise modular synthesis and structure-property study of acid-cleavable star-block copolymers for pH-triggered drug delivery”. Polym. Chem., 2015, 6, 1553-1566.

(20)Hairong Wang,Jinlin He, Dongling Cao, Mingzu Zhang, Fei Li, Kam Chiu Tam and Peihong Ni*, “Synthesis of an acid-labile polymeric prodrug DOX-acetal-PEG-acetal-DOX with high drug loading content for pH-triggered intracellular drug release”, Polym. Chem., 2015, 6, 4809-4818.

(21)Hairong Wang, Jinlin He, Mingzu Zhang, Kam Chiu Tam*, Peihong Ni*, “A new pathway towards polymer modified cellulose nanocrystals via a “grafting onto” process for drug delivery”, Polym. Chem., 2015, 6, 4206-4209.

(22)Dazhao Wu, Jinlin He, Mingzu Zhang*, Peihong Ni, Xiaofei Li, Jiankang Hu, “Fabrication of a novel sandwich-like composite separator with enhanced physical and electrochemical performances for lithium-ion battery”, J. Power Sources, 2015, 290, 53-60.

(23)Xiaofei Li, Jinlin He, Dazhao Wu, Mingzu Zhang*, Juwen Meng, Peihong Ni, “Development of plasma-treated polypropylene nonwoven-based composites for high-performance lithium-ion battery separators”,Electrochim. Acta, 2015, 167, 396-403.

(24)Xingqiang Huang, Jinlin He, Ying Hao, Min Ye, Qi Zhang, Peihong Ni, Jian Liu*, “Synthesis of PEGylated brush-type copolymers for a plurality of plug-and-play functions”, RSC Adv., 2015, 5, 50019-50023.

(25)Yang Zhang, Jinlin He*, Dongling Cao, Mingzu Zhang, Peihong Ni*, “Galactosylated reduction and pH dual-responsive triblock terpolymer Gal-PEEP-a-PCL-ss-PDMAEMA: a multifunctional carrier for targeted and simultaneous delivery of doxorubicin and DNA”. Polym. Chem., 2014, 5, 5124-5138.

(26)Jiao Bian, Ying Hao, Jinlin He*, Wenling Zhang, Mingzu Zhang, Peihong Ni*, “Synthesis and characterization of a biodegradable ABC triblock terpolymer as co-delivery carrier of doxorubicin and DNA”. J. Polym. Sci., Part A: Polym. Chem., 2014, 52, 3005-3016.

(27)Wen-Bin Zhang,Jinlin He, Kan Yue, Chang Liu, Peihong Ni, Roderic P. Quirk,* Stephen Z. D. Cheng*. “Rapid and efficient anionic synthesis of well-defined eight-arm star polymers using octavinylPOSS and poly(styryl)lithium”. Macromolecules, 2012, 45, 8571-8579. (共同第一作者)

(28)Jinlin He, Mingzu Zhang, Peihong Ni*. “Rapidly in situ forming polyphosphoester-based hydrogels for injectable drug delivery carriers”. Soft Matter, 2012, 8, 6033-6038.

(29)Jinlin He, Kan Yue,Yuqing Liu, Xinfei Yu, Peihong Ni, Kevin A. Cavicchi,Roderic P. Quirk, Erqiang Chen*, Stephen Z. D. Cheng*, Wen-Bin Zhang*. “Fluorinated polyhedral oligomeric silsesquioxane-based shape amphiphiles: Molecular design, topological variance, and facile synthesis”. Polym. Chem., 2012, 3, 2112-2120. (共同第一作者)

(30)Jinlin He, Haiyan Shao, Mingzu Zhang, Peihong Ni*, “Novel pH-responsive polyphosphoester-based hydrogels with fast gelation”. J. Controlled Release, 2011, 152, e232-e233.

(31)Jinlin He, Peihong Ni*, Sai Wang, Haiyan Shao, Mingzu Zhang, Xiulin Zhu*. “Synthesis and physicochemical characterization of biodegradable and pH-responsive hydrogels based on polyphosphoester for protein delivery”. J. Polym. Sci., Part A: Polym. Chem., 2010, 48, 1919-1930.

(32)Jinlin He, Peihong Ni*, Cuicui Liu. “Synthesis and characterization of amphiphilic fluorinated pentablock copolymers based on Pluronic F127”. J. Polym. Sci., Part A: Polym. Chem., 2008, 46, 3029-3041.

(33)何金林, 顾子旭, 梁骏, 倪沛红*,“壳聚糖接枝PDMAEMA共聚物的聚集行为”. 高分子材料科学与工程2008, 24(12), 126-129.

(34)胡健,何金林,张明祖, 倪沛红*. “点击化学在拓扑结构聚合物合成中的应用”, 高分子学报, 2013, 3, 300-319. (共同第一作者)

(35)Ying Hao, Jinlin He, Sen Li, Jian Liu, Mingzu Zhang, Peihong Ni*, “Synthesis of acid-cleavable and fluorescent amphiphilic block copolymer as a combined delivery vector of DNA and doxorubicin”, J. Mater. Chem. B, 2014, 2, 4237-4249.

(36)Yunfeng Tao, Jinlin He, Mingzu Zhang, Ying Hao, Jian Liu, Peihong Ni*. “Galactosylated biodegradable poly(ε-caprolactone-co-phosphoester) random copolymer nanoparticles for potent hepatoma-targeting delivery of doxorubicin”, Polym. Chem., 2014, 5, 3443-3452.

(37)Hairong Wang, Jinlin He, Mingzu Zhang, Yunfeng Tao, Fei Li, Kam Chiu Tam, Peihong Ni*. “Biocompatible and acid-cleavable poly(ε-caprolactone)-acetal-poly(ethylene glycol)-acetal-poly(ε-caprolactone) triblock copolymers: synthesis, characterization and pH-triggered doxorubicin delivery”, J. Mater. Chem. B, 2013, 1, 6596-6607. (内封面文章)

(38)肖燕, 何金林, 陶云锋, 张明祖, 胡健, 倪沛红*. “基于功能化聚磷酸酯嵌段共聚物的微凝胶和水凝胶的制备与表征”, 高分子学报, 2014, 1, 122-130.

(39)Ying Hao, Jinlin He, Mingzu Zhang, Yunfeng Tao, Jian Liu, Peihong Ni*. “Synthesis and characterization of novel brush copolymers with biodegradable polyphosphoester side chains for gene delivery”. J. Polym. Sci., Part A: Polym. Chem., 2013, 51, 2150-2160.

(40)Kan Yue, Jinlin He, Chang Liu, Mingjun Huang, Xue-Hui Dong, Kai Guo, Peihong Ni, Chrys Wesdemiotis, Roderic P. Quirk,*Stephen Z. D. Cheng,* Wen-Bin Zhang*. “Anionic synthesis of a “Clickable” middle-chain azide-functionalized polystyrene and its application in shape amphiphiles”. Chinese J. Polym. Sci.,2013, 31(1), 71-82.

(41)Wen-Bin Zhang, Jinlin He, Xuehui Dong, Chien-Lung Wang, Hui Li, Fuai Teng, Xiaopeng Li, Chrys Wesdemiotis, Roderic P. Quirk*, Stephen Z.D. Cheng*. “Improved synthesis of fullerynes by Fisher esterification for modular and efficient construction of fullerene polymers with high fullerene functionality”. Polymer, 2011, 52, 4221-4226.

(42)Wenling Zhang, Jinlin He, Zhuang Liu, Peihong Ni*, Xiulin Zhu*. “Biocompatible and pH-responsive triblock copolymer mPEG-b-PCL-b-PDMAEMA: Synthesis, self-assembly and application”. J. Polym. Sci., Part A: Polym. Chem., 2010, 48, 1079-1091.

(43)Mingzu Zhang, Jinlin He, Jiang Mao, Cuicui Liu, Hairong Wang, Yinfeng Huang, Peihong Ni*. “Kinetics of styrene miniemulsion polymerization using poly[(stearyl methacrylate-co-(N, N-dimethylamino)ethyl methacrylate] as surfactant”. Colloid. Surface. A: Physicochem. Eng. Asp.,2010, 360, 190-197.

(44)Cuicui Liu, Jinlin He, Qun Zhao, Mingzu Zhang, Peihong Ni*. “Well-defined poly[(dimethylamino)ethyl methacrylate]-b-poly(fluoroalkyl methacrylate) diblock copolymers: Effects of different fluoroalkyl groups on the solution properties”, J. Polym. Sci., Part A: Polym. Chem., 2009, 47, 2702-2712.

(45)Xiaofei Li, Mingzu Zhang*, Jinlin He, Dazhao Wu, Juwen Meng, Peihong Ni. “Effects of fluorinated SiO2 nanoparticles on the thermal and electrochemical properties of PP nonwoven/PVdF-HFP composite separator for Li-ion batteries”, J. Membr. Sci., 2014, 455, 368-374.

(46)郝莹, 张洋, 何金林, 尚修娟, 张明祖, 倪沛红*. “半乳糖胺修饰阳离子型刷形嵌段共聚物的合成与表征”, 化学学报, 2014, 72, 569-576.

(47)Guoyi Zhang, Mingzu Zhang, Jinlin He, Peihong Ni*. “Synthesis and characterization of a new multifunctional polymeric prodrug paclitaxel-polyphosphoester-folic acid for targeted drug delivery”, Polym. Chem., 2013, 4, 4515-4525.

(48)Ying Hao, Mingzu Zhang, Jinlin He, Peihong Ni*. “Magnetic DNA vector constructed from PDMAEMA polycation and PEGylated brush-type polyanion with cross-linkable shell”. Langmuir, 2012, 28, 6448-6460.

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