Name:LI Dan
Title:Associate Professor

Tel +86-0512-65880567


Group Website


B.Sc.         Wuhan University of Technology, 2002.09-2006.07 (Polymer Material Science and Engineering)

Ph.D.         Wuhan University of Technology, 2006.09-2011.07 (Biomaterial Science)

Visiting student      McMaster University, 2007.09-2008.09



Surface modification of blood-contact materials; research on protein/surface interactions



1)         Li D, Chen H, Brash JL*. Mimicking the fibrinolytic system on material surfaces. Colloids and Surfaces B: Biointerfaces 2011;86:1-6.

2)         Li D, Chen H*, McClung WG, Brash JL. Lysine-PEG-modified polyurethane as a fibrinolytic surface: Effect of PEG chain length on protein interactions, platelet interactions and clot lysis. Acta Biomaterialia 2009;5:1864-71.

3)         Li D, Chen H*, Wang S, Wu Z, Brash JL. Lysine-poly(2-hydroxyethyl methacrylate) modified polyurethane surface with high lysine density and fibrinolytic activity. Acta Biomaterialia 2011;7:954-8.

4)         Li D, Wang S, Wu Z, Chen H*, Brash JL. A new t-PA releasing concept based on protein-protein displacement. Soft Matter 2013;9:2321-8.

5)         Li D, Zheng Q, Wang Y, Chen H*. Combining surface topography with polymer chemistry: exploring new interfacial biological phenomena. Polymer Chemistry 2014;5:14-24.

6)         Luan YF, Li D*, Wang YW, Liu XL, Brash JL, Chen H*. I-125-Radiolabeling, Surface Plasmon Resonance, and Quartz Crystal Microbalance with Dissipation: Three Tools to Compare Protein Adsorption on Surfaces of Different Wettability. Langmuir 2014;30:1029-35.

7)         Tang Z, Liu X, Luan Y, Liu W, Wu Z, Li D*, Chen H*. Regulation of fibrinolytic protein adsorption on polyurethane surfaces by modification with lysine-containing copolymers. Polymer Chemistry 2013;4:5597-602.

8)         Xu H, Luan Y, Wu Z, Li X, Yuan Y, Liu X, Yuan L, Li D*, Chen H*. Incorporation of Lysine-Containing Copolymer with Polyurethane Affording Biomaterial with Specific Adsorption of Plasminogen. Chinese Journal of Chemistry 2014;32:44-50.

9)         Yang W, Tang Z, Luan Y, Liu W, Li D*, Chen H*. Thermoresponsive Copolymer Decorated Surface Enables Controlling the Adsorption of a Target Protein in Plasma. ACS Applied Materials & Interfaces 2014;6:10146-52.

10)     Zheng J, Li D*, Yuan L, Liu X, Chen H*. Lotus-Leaf-Like Topography Predominates over Adsorbed ECM Proteins in Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) Surface/Cell Interactions. ACS Applied Materials & Interfaces 2013;5:5882-7.

11)     Tang Z, Li D*, Wang X, Gong H, Luan Y, Liu Z, Brash JL, Chen H*. A t-PA/nanoparticle conjugate with fully retained enzymatic activity and prolonged circulation time. Journal of Materials Chemistry B 2015;3:977-82.

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