Name:NI Peihong
Title:Professor
Department:
Contacts:

Professor in Macromolecular Science

College of Chemistry, Chemical Engineering and Materials Science

Soochow University

SuzhouJiangsu215123China

Tel: 86-512-65882047

E-mail: phni@suda.edu.cn


Group Website

Education Background:

PhD in Polymer Chemistry, Fudan University, China, 2001

MSc in Organic Chemistry, Soochow University, China, 1988

BSc in Polymer Chemistry, Nanjing University, China, 1982

 

Professional Experience:         

2003---:         Professor, College of Chemistry, Chemical Engineering and Materials Science, China

1998-1999:   Visiting Scholar, Coatings Research Institute, Eastern Michigan University, USA

1996---2003: Associate Professor, Department of Chemistry, Soochow University, China.

1988---1996: Assistant Professor, Department of Chemistry, Soochow University, China.

 

Research Interests:

w   Design and Synthesis of Stimuli-Responsive Copolymers (Block Copolymers and Hydrogels for Gene and Drug Delivery)

w   Fluorocarbon-Hydrocarbon hybrid Amphiphilic Copolymers

w   Emulsion and Miniemulsion Polymerization

w   Modification and Application of Natural Polymers

 

Research Experience and Accomplishments:

Professor Peihong Ni’s group focuses on synthesizing biocompatible and stimuli-responsive polymers for biomedical applications, fluorocarbon-hydrocarbon hybrid amphiphilic copolymers with controlled structure, as well as (mini)emulsion polymerization with functional particle surface. She has published more than 80 peered-reviewed articles and three book chapters, and held 17 authorized patents of China.

 

Recent Publications: (2008-2015)

1.       Kai Ren, Mingzu Zhang, Jinlin He, Yixian Wu, Peihong Ni*, “Polymeric prodrug paclitaxel-poly(lactic acid)-b-polyisobutylene and its application in coatings of drug eluting stent”, ACS Applied Materials & Interfaces, 2015, 10.1021/acsami.5b01410.

2.       Qingqing Zhang, Jinlin He*, Mingzu Zhang, Peihong Ni*, “Polyphosphoester-conjugated camptothecin prodrug with disulfide linkage for potent reduction-triggered drug delivery”, Journal of Materials Chemistry B, 2015, DOI: 10.1039/C5TB00623F.

3.       Hairong Wang, Jinlin He, Mingzu Zhang, Kam Chiu Tam*, Peihong Ni*, “A new pathway towards polymer modified cellulose nanocrystals via a “grafting onto” process for drug delivery”, Polymer Chemistry, 2015, DOI: 10.1039/C5PY00466G.

4.       Jian Hu, Jinlin He, Dongling Cao, Mingzu Zhang, Peihong Ni*, “Core cross-linked polyphosphoester micelles with folate-targeted and acid-cleavable features for pH-triggered drug delivery”, Polymer Chemistry, 2015, 6, 3205 -3216. (Front cover article)

5.       Jian Hu, Jinlin He*, Mingzu Zhang, Peihong Ni*, “Precise modular synthesis and a structure–property study of acid-cleavable star-block copolymers for pH-triggered drug delivery”, Polymer Chemistry, 2015, 6, 1553-1566.

6.       Jiao Bian, Ying Hao, Jinlin He*, Wenling Zhang, Mingzu Zhang, Peihong Ni*, “Synthesis and characterization of a biodegradable ABC triblock terpolymer for co-delivery carrier of doxorubicin and DNA”, Journal of Polymer Science, Part A: Polymer Chemistry, 2014, 52, 3005–3016.

7.       Sen Li, Ming-zu Zhagn, Jinlin He, Peihong Ni*, “Film properties of fluorinated polymethacrylate/polyisobutylene based block copolymers”, ACTA Polymerica Sinica, 2014, 12, 1648-1658.

8.       Yang Zhang, Jinlin He*, Dongling Cao, Mingzu Zhang, Peihong Ni*, “Galactosylated reduction and pH dual-responsive triblock terpolymer Gal-PEEP-a-PCL-ss-PDMAEMA : a Multifunctional carrier for the targeted and simultaneous delivery of doxorubicin and DNA”, Polymer Chemistry, 2014, 5, 5124-5138.

9.       Ying Hao, Yang Zhang, Jinlin He, Xiujuan Shang, Mingzu Zhang, Peihong Ni*, “Synthesis and characterization of PEGylated brush-type polycation modified with galactosamine”, Acta Chim. Sinica, 2014, 72, 569-576.

10.    Ying Hao, Jinlin He, Sen Li, Jian Liu, Mingzu Zhang, Peihong Ni*, “Synthesis of an acid-cleavable and fluorescent amphiphilic block copolymer as a combined delivery vector of DNA and doxorubicin”, Journal of Materials Chemistry B, 2014, 2, 4237-4249. 

11.    Yunfeng Tao, Jinlin He, Mingzu Zhang, Jian Liu, Peihong Ni*, “Galactosylated biodegradable poly(e-caprolactone-co-phosphoester) random copolymer nanoparticles for potent hepatoma-targeting delivery of doxorubicin”, Polymer Chemistry, 2014, 5, 3443-3452.

12.    Yan Xiao, Jinlin He, Yunfeng Tao, Mingzu Zhang, Jian Hu, Peihong Ni, “Preparation and characterization of microgels and hydrogels based on functional polyphosphoester diblock copolymers”, ACTA Polymerica Sinica, 2014, 1, 122-130.

13.    Hairong Wang, Jinlin He, Mingzu Zhang, Yunfeng Tao, Fei Li, Kam C. Tam, Peihong Ni*, Biocompatible and acid-cleavable poly(ε-caprolactone)-acetal-poly(ethylene glycol)-acetal-poly(ε-caprolactone) triblock copolymers: Synthesis, characterization and pH-triggered doxorubicin delivery”, Journal of Materials Chemistry B, 2013, 1, 6596-6607. (Front inside cover article)

14.    Guoyi Zhang, Mingzu Zhang, Jinlin He, Peihong Ni*, “Synthesis and characterization of a new multifunctional polymeric prodrug paclitaxel-polyphosphoester-folic acid for targeted drug delivery”, Polymer Chemistry, 2013, 4, 4515-4525.

15.    Ying Hao, Jinlin He, Mingzu Zhang, Yunfeng Tao, Jian Liu, Peihong Ni*, “Synthesis and characterization of novel brush copolymers with biodegradable polyphosphoester side chains for gene delivery”, Journal of Polymer Science, Part A: Polymer Chemistry, 2013, 51, 2150-2160. (Spotlight on Polymer Chemistry Issue 10, http://www.materialsviews.com/spotlight-on-polymer-chemistry-volume-51-issue-10/

16.    Jiao Bian, Mingzu Zhang, Jinlin He, Peihong Ni*, “Preparation and self-Assembly of double hydrophilic poly(ethylethylene phosphate)-block-poly[2-(succinyloxy)ethyl methacrylate] diblock copolymers for drug delivery”, Reactive & Functional Polymers, 2013, 73, 579-587.

17.    Huaichao Wang, Mingzu Zhang, Peihong Ni*, Jinlin He, Ying Hao, Yixian Wu, “Synthesis of pH-responsive amphiphilic diblock copolymers containing polyisobutylene via oxyanion-initiated polymerization and their multiple self-assembly morphologies”, Chinese Journal of Polymer Science, 2013, 31 (2), 218-231. Cover article.

18.    Jinlin He, Mingzu Zhang, Peihong Ni*, “Rapidly in situ forming polyphosphoester-based hydrogels for injectable drug delivery carriers”. Soft Matter, 2012, 8, 6033-6038.

19.    Ying Hao, Mingzu Zhang, Jinlin He, Peihong Ni*, “Magnetic DNA vector constructed from PDMAEMA polycation and PEGylated brush-type polyanion with crosslinkable shell”, Langmuir, 2012, 28, 6448-6460.

20.    Haiyan Shao, Mingzu Zhang, Jinlin He, Peihong Ni*, Synthesis and characterization of amphiphilic poly(e-caprolactone)-b-polyphosphoester diblock copolymers bearing multifunctional pendant groups”, Polymer, 2012, 53, 2854-2863.

21.    Shihua Zhang, Zixu Gu, Ying Hao, Mingzu Zhang, Peihong Ni*, “Synthesis of double-hydrophilic block copolymers via combination of oxyanion-initiated polymerization and polymer reaction for fabricating magnetic target gene carrier”, Journal of Polymer Science, Part A: Polymer Chemistry, 2011, 49, 4081-4091.

22.    Zhang, Shihua; Zhu huiwen, Zhang Mingzu; Ni Peihong. Synthesis and properties of Fe3O4@SiO2-g-PDMAEMA Prepared via combination of atom transfer radical polymerization and “Click” reaction”, Acta Chimica Sinica, 2011, 69, 2166-2172.

23.    Xu Liu, Peihong Ni*, Jinlin He, Mingzu Zhang, “Synthesis and micellization of pH/temperature-responsive double-hydrophilic diblock copolymers polyphosphoester- block-poly[2-(dimethylamino)ethyl methacrylate] prepared via ROP and ATRP”, Macromolecules, 2010, 43, 4771-4781.

24.    Yaojuan Wu, Peihong Ni*, Mingzu Zhang, Xiulin Zhu*, “Fabrication of microgels via supramolecular assembly of cyclodextrin-containing star polycations and oppositely charged linear polyanions”, Soft Matter, 2010, 6, 3751-3758.

25.    Jinlin He, Peihong Ni,* Sai Wang, Haiyan Shao, Mingzu Zhang, Xiulin Zhu*, “Synthesis and physicochemical characterization of biodegradable and pH-responsive hydrogels based on polyphosphoester for protein delivery”, Journal of Polymer Science, Part A: Polymer Chemistry, 2010, 48, 1919-1930.

26.    Wenling Zhang, Jinlin He, Zhuang Liu, Peihong Ni,* Xiulin Zhu*, “Biocompatible and pH-responsive triblock copolymer mPEG-b-PCL-b-PDMAEMA: Synthesis, self-assembly and application”, Journal of Polymer Science, Part A: Polymer Chemistry, 2010, 48, 1079-1091.

27.    Mingzu Zhang, Jinlin He, Jiang Mao, Cuicui Liu, Hairong Wang, Yinfeng Huang, Peihong Ni*, “Kinetics of styrene miniemulsion polymerization using poly[(stearyl methacrylate-co-(N, N-dimethylamino)ethyl methacrylate] as surfactant”, Colloids and Surfaces A: Physicochem. Eng. Aspects, 2010, 360, 190-197.

28.    Ying Hao, Mingzu Zhang, Jie Xu, Cuicui Liu, Peihong Ni*, “Synthesis and micellization of triblock copolymers containing MePEG-b-PDMAEMA and fluoropolymer: Effect of block lengths on self-assembly”, Journal of Macromolecular Science A-Pure and Applied Chemistry, 2010, 47, 941-951.

29.    Yuan Yuan; Zhang Mingzu; Zhang Hu; Ni Peihong*. “Synthesis and Properties of pH-responsive fluorinated amphiphilic triblock copolymers”, Acta Chimica Sinica, 2010, 68(15), 1537-1544.

30.    Zixu Gu, Yuan Yuan, Jinlin He, Mingzu Zhang, Peihong Ni*, “Facile approach for DNA encapsulation in functional polyion complex for triggered intracellular gene delivery: Design, synthesis, and mechanism”, Langmuir, 2009, 25, 5199-5208.

31.    Guixiang Sun, Mingzu Zhang, Jinlin He, Peihong Ni*, “Synthesis of amphiphilic cationic copolymers poly[2-(methacryloyloxy)ethyl trimethylammonium chloride-co-stearyl methacrylate] and their self-assembly behavior in water and water-ethanol mixtures”, Journal of Polymer Science, Part A: Polymer Chemistry, 2009, 47, 4670-4684.

32.    Cuicui Liu, Jinlin He, Qun Zhao, Mingzu Zhang, Peihong Ni*, “Well-defined poly[(dimethylamimo)ethyl methacrylate]-b-poly(fluoroalkyl methacrylate) diblock copolymers: Effects of different fluoroalkyl groups on the solution properties”, Journal of Polymer Science, Part A: Polymer Chemistry, 2009, 47, 2702-2712.

33.    Cuicui Liu, Peihong Ni*, Xiao Fang, Xiaodong Zhou, “Synthesis of amphiphilic diblock copolymers poly[2-(N, N-dimethylamino)ethyl methacrylate]-b-poly(stearyl methacrylate) and their self-assembly in mixed solvent”, Colloid & Polymer Science, 2009, 287, 45-55.

34.    Hu Zhang, Peihong Ni*, Jinlin He, Cuicui Liu,Novel fluoroalkyl end-capped amphiphilic diblock copolymers with pH/temperature response and self-assembly behavior”, Langmuir, 2008, 24, 4647-4654.

35.    Jinlin He, Peihong Ni*, Cuicui Liu, “Synthesis and characterization of amphiphilic fluorinated pentablock copolymers based on Pluronic F127”, Journal of Polymer Science, Part A: Polymer Chemistry, 2008, 46, 3029-3041.

 

Book Chapters:

1.       Peihong Ni, Shoukuan Fu, “Chapter 3: Preparation of Microlatexes Using Polymeric Surfactants or Mixed Surfactants”, in Colloid Polymers: Synthesis and Characterization, Edited by Abdelhamid Elaïssari, Surfactant Science Series (Volume115). Published by Marcel Dekker, Inc., New York, p47-76, 2003.

2.       Peihong Ni, Chapter 2: Nanoparticles Comprising pH/Temperature-Responsive Amphiphilic Block Copolymers and Their Applications in Biotechnology”, in Colloidal Nanoparticles in Biotechnology, Edited by Abdelhamid Elaïssari, Copyright Ó 2008 John Wiley & Sons, Inc. p31-63, 2008.

3.       Peihong Ni*, Xiulin Zhu, Xiaodong Zhou, “Chapter 19: Kinetics and colloidal stability of RAFT/miniemulsion polymerization of MMA using comblike polymeric surfactants”, in Controlled/Living Radical Polymerization: Progress in RAFT, DT, NMP & OMRP; Edited by Krzysztof Matyjaszewski; ACS Symposium Series 1024; Copyright Ó 2009 American Chemical Society, Oxford University Press, p293-302, 2009.


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