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倪沛红
  姓名：倪沛红
  职称：教授、博士生导师

  部门：材料学院
  联系方式：
    Professor in Macromolecular Science

    College of Chemistry, Chemical Engineering and Materials Science

    Soochow University

    Suzhou，Jiangsu，215123，China 

    Tel: 86-512-65882047
    E-mail: phni@suda.edu.cn


 课题组网站

学历及学术经历:

1982年毕业于南京大学化学系高分子化学专业，1988年获苏州大学有机化学专业硕士学位，留校在化学系任教。1997.9-2000.12，复旦大学高分子科学系攻读博士学位。其间，1998.9-1999.10，美国东密歇根大学访问学者。2000年获复旦大学高分子化学与物理专业博士学位。2003年被聘为苏州大学教授、高分子化学与物理专业博士生导师。主持完成国家自然科学基金面上项目4项，省部级项目5项。在Macromolecules、ACS Applied Materials & Interfaces、Journal of Materials Chemistry B、Polymer Chemistry、Soft Matter、Langmuir、J. Polym. Sci. Part A: Polym. Chem. 等刊物发表研究论文110多篇，撰写英文著作3章，获授权的中国发明专利25项。

  

研究领域:

(1)设计合成环境响应性生物医用高分子材料；(2) 氟碳－碳氢杂化的两亲性聚合物及其应用; (3) 乳液及细乳液聚合；(4) 天然高分子的改性。


代表性论文：

  1. Youwen Cao, Jinlin He, Jie Liu, Mingzu Zhang, Peihong Ni*, “Folate-conjugated polyphosphoester with reversible cross-linkage and reduction sensitivity for drug delivery”, ACS Applied Materials & Interfaces, 2018, 10 (9), 7811-7820.

  2. Xueqiong Du, Yue Sun, Mingzu Zhang, Jinlin He and Peihong Ni*, “Polyphosphoester-camptothecin prodrug with reduction-response prepared via michael addition polymerization and click reaction”, ACS Applied Materials & Interfaces, 2017, 9, 13939-13949.

  3. Yue Sun, Xueqiong Du, Jinlin He, Jian Hu, Mingzu Zhang and Peihong Ni*, “Dual-responsive core-crosslinked polyphosphoester-based nanoparticles for pH/redox-triggered anticancer drug delivery”, Journal of Materials Chemistry B, 2017, 5, 3771-3782.

  4. Zixu Gu, Jun Cheng, Mingzu Zhang, Jinlin He, Peihong Ni*, “Effect of Sequence structure on wetting behaviors of fluorinated methacrylate polymers based on perfluorohexylethyl methacrylate and stearyl acrylate”, Chinese Journal of Polymer Science,2017, 35(9), 1061-1072.

  5. Zixu Gu, Jun Cheng, Mingzu Zhang, Jinlin He, Peihong Ni *, “Effect of groups at α-position and side-chain structure of comonomers on surface energy and surface reorganization of fluorinated methacrylate copolymer”, Polymer, 2017, 114, 79-87.

  6. Dongling Caoa, Jinlin Hea, Jiaying Xub, Mingzu Zhanga, Lin Zhaob, Guangxin Duanb, Youwen Caoa, RuhongZhoub,c,d,* and Peihong Ni a,*, “Polymeric prodrugs conjugated with reduction-sensitive dextran-camptothecin and pH-responsive dextran-doxorubicin: An effective combinatorial drug delivery platform for cancer therapy”, Polymer Chemistry, 2016, 7, 4198-4212.

  7. Sen Li, Jinlin He*, Mingzu Zhang, Hairong Wang, Peihong Ni*, “Multicompartment morphologies self-assembled from fluorinated ABC triblock terpolymers: Effects of flexible and rigid hydrophobic moieties”, Polymer Chemistry, 2016, 7, 1773-1781.

  8. Kai Ren, Mingzu Zhang, Jinlin He, Yixian Wu, Peihong Ni*, “Polymeric prodrug paclitaxel-poly(lactic acid)-b-polyisobutylene and its application in coatings of drug eluting stent”, ACS Applied Materials & Interfaces, 2015, 7(21), 11263–11271.

  9. Qingqing Zhang, Jinlin He*, Mingzu Zhang, Peihong Ni*, “Polyphosphoester-conjugated camptothecin prodrug with disulfide linkage for potent reduction-triggered drug delivery”, Journal of Materials Chemistry B, 2015, 3, 4922-4932.

  10. Hairong Wang, Jinlin He, Mingzu Zhang, Kam Chiu Tam*, Peihong Ni*, “A new pathway towards polymer modified cellulose nanocrystals via a “grafting onto” process for drug delivery”, Polymer Chemistry, 2015, 6, 4206-4209..

  11. Jian Hu, Jinlin He, Dongling Cao, Mingzu Zhang, Peihong Ni*, “Core cross-linked polyphosphoester micelles with folate-targeted and acid-cleavable features for pH-triggered drug delivery”, Polymer Chemistry, 2015, 6, 3205 -3216. (Front cover article)

  12. Jian Hu, Jinlin He*, Mingzu Zhang, Peihong Ni*, “Precise modular synthesis and a structure–property study of acid-cleavable star-block copolymers for pH-triggered drug delivery”, Polymer Chemistry, 2015, 6, 1553-1566.

  13. 胡健，何金林，张明祖，倪沛红*. “聚磷酸酯的合成及在生物医用材料中的应用”, 《高分子通报》, 2015, 10, 51-65.

  14. Jiao Bian, Ying Hao, Jinlin He*, Wenling Zhang, Mingzu Zhang, Peihong Ni*, “Synthesis and characterization of a biodegradable ABC triblock terpolymer for co-delivery carrier of doxorubicin and DNA”, Journal of Polymer Science, Part A: Polymer Chemistry, 2014, 52, 3005–3016.

  15. Yang Zhang, Jinlin He*, Dongling Cao, Mingzu Zhang, Peihong Ni*, “Galactosylated reduction and pH dual-responsive triblock terpolymer Gal-PEEP-a-PCL-ss-PDMAEMA : a Multifunctional carrier for the targeted and simultaneous delivery of doxorubicin and DNA”, Polymer Chemistry, 2014, 5, 5124-5138.

  16. Ying Hao, Jinlin He, Sen Li, Jian Liu, Mingzu Zhang, Peihong Ni*, “Synthesis of an acid-cleavable and fluorescent amphiphilic block copolymer as a combined delivery vector of DNA and doxorubicin”, Journal of Materials Chemistry B, 2014, 2, 4237-4249.

  17. Yunfeng Tao, Jinlin He, Mingzu Zhang, Jian Liu, Peihong Ni*, “Galactosylated biodegradable poly(e-caprolactone-co-phosphoester) random copolymer nanoparticles for potent hepatoma-targeting delivery of doxorubicin”, Polymer Chemistry, 2014, 5, 3443-3452.

  18. 肖燕，何金林，陶云锋，张明祖，胡健，倪沛红*.“基于功能化聚磷酸酯嵌段共聚物的微凝胶和水凝胶的制备与表征”,《高分子学报》, 2014, 1, 122-130.

  19. 李森，张明祖，何金林，倪沛红*. “含氟聚甲基丙烯酸酯/聚异丁烯嵌段共聚物的成膜性质研究”, 《高分子学报》, 2014, 12, 1648-1658.

  20. 郝莹，张洋，何金林，尚修娟，张明祖，倪沛红*. “半乳糖胺修饰阳离子型刷形嵌段共聚物的合成与表征”, 《化学学报》, 2014, 72, 569-576.

  21. Hairong Wang, Jinlin He, Mingzu Zhang, Yunfeng Tao, Fei Li, Kam C. Tam, Peihong Ni*, “Biocompatible and acid-cleavable poly(ε-caprolactone)-acetal-poly(ethylene glycol)-acetal-poly(ε-caprolactone) triblockcopolymers: Synthesis, characterization and pH-triggered doxorubicin delivery”, Journal of Materials Chemistry B, 2013, 1, 6596-6607. (Front inside cover article)

  22. Guoyi Zhang, Mingzu Zhang, Jinlin He, Peihong Ni*, “Synthesis and characterization of a new multifunctional polymeric prodrug paclitaxel-polyphosphoester-folic acid for targeted drug delivery”,Polymer Chemistry, 2013, 4, 4515-4525.

  23. Ying Hao, Jinlin He, Mingzu Zhang, Yunfeng Tao, Jian Liu, Peihong Ni*, “Synthesis and characterization of novel brush copolymers with biodegradable polyphosphoester side chains for gene delivery”, Journal of Polymer Science, Part A: Polymer Chemistry, 2013, 51, 2150-2160. (Spotlight on Polymer Chemistry Issue 10, http://www.materialsviews.com/spotlight-on-polymer-chemistry-volume-51-issue-10/)

  24. Jiao Bian, Mingzu Zhang, Jinlin He, Peihong Ni*, “Preparation and self-Assembly of double hydrophilic poly(ethylethylene phosphate)-block-poly[2-(succinyloxy)ethyl methacrylate] diblock copolymers for drug delivery”, Reactive & Functional Polymers, 2013, 73, 579-587.

  25. Huaichao Wang, Mingzu Zhang, Peihong Ni*, Jinlin He, Ying Hao, Yixian Wu, “Synthesis of pH-responsive amphiphilic diblock copolymers containing polyisobutylene via oxyanion-initiated polymerization and their multiple self-assembly morphologies”, Chinese Journal of Polymer Science, 2013, 31 (2), 218-231. (Cover article)

  26. 胡健,‡ 何金林,‡ 张明祖, 倪沛红*. “点击化学在拓扑结构聚合物合成中的应用”, 《高分子学报》, 2013, 3, 300-319. (‡共同第一作者)

  27. Jinlin He, Mingzu Zhang, Peihong Ni*, “Rapidly in situ forming polyphosphoester-based hydrogels for injectable drug delivery carriers”. Soft Matter, 2012, 8, 6033-6038.

  28. Ying Hao, Mingzu Zhang, Jinlin He, Peihong Ni*, “Magnetic DNA vector constructed from PDMAEMA polycation and PEGylated brush-type polyanion with crosslinkable shell”, Langmuir, 2012, 28, 6448-6460.

  29. Haiyan Shao, Mingzu Zhang, Jinlin He, Peihong Ni*, “Synthesis and characterization of amphiphilic poly(e-caprolactone)-b-polyphosphoester diblock copolymers bearing multifunctional pendant groups”, Polymer,2012, 53, 2854-2863.

  30. Shihua Zhang, Zixu Gu, Ying Hao, Mingzu Zhang, Peihong Ni*, “Synthesis of double-hydrophilic block copolymers via combination of oxyanion-initiated polymerization and polymer reaction for fabricating magnetic target gene carrier”, Journal of Polymer Science, Part A: Polymer Chemistry, 2011, 49, 4081-4091.

  31. 张世华，朱慧文，张明祖，倪沛红*.“原子转移自由基聚合与“Click”反应相结合制备Fe3O4@SiO2-g-PDMAEMA及其性质研究”,《化学学报》, 2011, 69, 2166-2172.

  32. Xu Liu, Peihong Ni*, Jinlin He, Mingzu Zhang, “Synthesis and micellization of pH/temperature-responsive double-hydrophilic diblock copolymers polyphosphoester- block-poly[2-(dimethylamino)ethyl methacrylate] prepared via ROP and ATRP”, Macromolecules, 2010, 43, 4771-4781.

  33. Yaojuan Wu, Peihong Ni*, Mingzu Zhang, Xiulin Zhu*, “Fabrication of microgels via supramolecular assembly of cyclodextrin-containing star polycations and oppositely charged linear polyanions”, Soft Matter, 2010, 6, 3751-3758.

  34. Jinlin He, Peihong Ni,* Sai Wang, Haiyan Shao, Mingzu Zhang, Xiulin Zhu*, “Synthesis and physicochemical characterization of biodegradable and pH-responsive hydrogels based on polyphosphoester for protein delivery”, Journal of Polymer Science, Part A: Polymer Chemistry, 2010, 48, 1919-1930.

  35. Wenling Zhang, Jinlin He, Zhuang Liu, Peihong Ni,* Xiulin Zhu*, “Biocompatible and pH-responsive triblock copolymer mPEG-b-PCL-b-PDMAEMA: Synthesis, self-assembly and application”, Journal of Polymer Science,Part A: Polymer Chemistry, 2010, 48, 1079-1091.

  36. Mingzu Zhang, Jinlin He, Jiang Mao, Cuicui Liu, Hairong Wang, Yinfeng Huang, Peihong Ni*, “Kinetics of styrene miniemulsion polymerization using poly[(stearyl methacrylate-co-(N, N-dimethylamino)ethyl methacrylate] as surfactant”, Colloids and Surfaces A: Physicochem. Eng. Aspects, 2010, 360, 190-197.

  37. Ying Hao, Mingzu Zhang, Jie Xu, Cuicui Liu, Peihong Ni*, “Synthesis and micellization of triblock copolymers containing MePEG-b-PDMAEMA and fluoropolymer: Effect of block lengths on self-assembly”, Journal of Macromolecular Science A-Pure and Applied Chemistry, 2010, 47, 941-951.

  38. 袁媛，张明祖，张虎，倪沛红*.“pH 响应性含氟三嵌段共聚物的制备及性质研究”, 《化学学报》, 2010, 68(15), 1537-1544.

  39. Zixu Gu, Yuan Yuan, Jinlin He, Mingzu Zhang, Peihong Ni*, “Facile approach for DNA encapsulation in functional polyion complex for triggered intracellular gene delivery: Design, synthesis, and mechanism”,Langmuir, 2009, 25, 5199-5208.

  40. Guixiang Sun, Mingzu Zhang, Jinlin He, Peihong Ni*, “Synthesis of amphiphilic cationic copolymers poly[2-(methacryloyloxy)ethyl trimethylammonium chloride-co-stearyl methacrylate] and their self-assembly behavior in water and water-ethanol mixtures”, Journal of Polymer Science, Part A: Polymer Chemistry, 2009, 47, 4670-4684.

  41. Cuicui Liu, Jinlin He, Qun Zhao, Mingzu Zhang, Peihong Ni*, “Well-defined poly[(dimethylamimo)ethyl methacrylate]-b-poly(fluoroalkyl methacrylate) diblock copolymers: Effects of different fluoroalkyl groups on the solution properties”, Journal of Polymer Science, Part A: Polymer Chemistry, 2009, 47, 2702-2712.

  42. Cuicui Liu, Peihong Ni*, Xiao Fang, Xiaodong Zhou, “Synthesis of amphiphilic diblock copolymers poly[2-(N, N-dimethylamino)ethyl methacrylate]-b-poly(stearyl methacrylate) and their self-assembly in mixed solvent”, Colloid & Polymer Science, 2009, 287, 45-55.

  43. Hu Zhang, Peihong Ni*, Jinlin He, Cuicui Liu, “Novel fluoroalkyl end-capped amphiphilic diblock copolymers with pH/temperature response and self-assembly behavior”, Langmuir, 2008, 24, 4647-4654.

  44. Jinlin He, Peihong Ni*, Cuicui Liu, “Synthesis and characterization of amphiphilic fluorinated pentablock copolymers based on Pluronic F127”, Journal of Polymer Science, Part A: Polymer Chemistry, 2008, 46, 3029-3041.

  

Book Chapters:

  1. Peihong Ni, Shoukuan Fu, “Chapter 3: Preparation of Microlatexes Using Polymeric Surfactants or Mixed Surfactants”, in Colloid Polymers: Synthesis and Characterization, Edited by Abdelhamid Elaïssari,Surfactant Science Series (Volume115). Published by Marcel Dekker, Inc., New York, p47-76, 2003.

  2. Peihong Ni, “Chapter 2: Nanoparticles Comprising pH/Temperature-Responsive Amphiphilic Block Copolymers and Their Applications in Biotechnology”, in Colloidal Nanoparticles in Biotechnology,Edited by Abdelhamid Elaïssari, Copyright Ó 2008 John Wiley & Sons, Inc. p31-63, 2008.

  3. Peihong Ni*, Xiulin Zhu, Xiaodong Zhou, “Chapter 19: Kinetics and colloidal stability of RAFT/miniemulsion polymerization of MMA using comblike polymeric surfactants”, in Controlled/Living Radical Polymerization: Progress in RAFT, DT, NMP & OMRP; Edited by Krzysztof Matyjaszewski; ACS Symposium Series 1024; Copyright Ó 2009 American Chemical Society, Oxford University Press, p293-302, 2009.