万小兵
  姓名:万小兵
  职称:教授、博士生导师

  部门:化学学院
  联系方式:
Tel:0512-65883276
Email:wanxb@suda.edu.cn
 课题组网站
学历及学术经历: 万小兵,理学博士,江苏泰州人。19977月于南京大学化学化工学院获学士学位,1998 9月至20017月,南京大学化学系攻读硕士学位,从事超分子化学的研究。2001 9月至20057月,中国科学院上海有机化学研究所攻读博士学位,系统研究了Ru/Rh 催化的不对称催化氢化反应,合成了一系列价格低廉、对映选择性高的手性双磷配体。2005 7月进入北京大学从事Pd 催化的C–H 键活化研究,取得了原创性的研究结果。20077月进入苏州大学工作,任职副教授。2012年破格聘为研究员,2014年遴选为博士生导师.主要从事绿色氧化反应,多组分反应,氟化学等领域的研究。迄今为止,已在JACSAngew. Chem.Org. Lett.JOCChem. Commun.Chem. Eur. J.Adv. Synth. Cat.等国际一流研究刊物发表论文数十篇,得到国内外同行的广泛关注与引用(引用近千次)。申请中国发明专利12项,已经授权4项。

研究领域: 绿色氧化反应,多组分反应,氟化学。发展绿色、环境友好的反应体系,合成具有重要的应用价值和具有生物活性的分子。

代表性论文
 
1.         Jie Zhang, Jiewen Jiang, Dongmei Xu, Qiang Luo, Hongxiang Wang, Jijun Chen, Huihuang Li, Yaxiong Wang, and Xiaobing Wan* Interception of Co-Based Carbene-Radical with α-Aminoalkyl Radicals: A New Tandem Reaction to Construct β-Ester-γ-Amino Ketone. Angew. Chem. Int. Ed. 2014, DOI: 10.1002/anie.201408874.
2.         Zhaojun Liu, Jie Zhang, Shulin Chen, Erbo Shi, Yuan Xu, and Xiaobing Wan,*Cross Coupling of Acyl and Aminyl Radicals: Direct Amides Synthesis Catalyzed by Bu4NI Using TBHP as an Oxidant. Angew. Chem. Int. Ed. 2012, 51, 3231–3235.
3.         Xiaobing Wan, Dong Xing, Zhao Fang, Bijie Li, Fei Zhao, Keya Zhang, Liping Yang, and Zhangjie Shi.* Multiple Deprotonations and Deaminations of Phenethylamines. An Unprecedented Apporach to Synthesize Pyrroles. J. Am. Chem. Soc.2006, 128, 12046–12047.
4.         Xiaobing Wan, Zhongxun Ma, Bijie Li, Keya Zhang, Shaokui Cao, Shiwei Zhang and Zhangjie Shi.* Highly Selective C-H Functionalization/Halogenation of Acetanilide. J. Am. Chem. Soc.2006, 128, 7416–7417.
5.         Zhang, Jie; Shao, Ying;*  Wang, Hongxiang;  Luo, Qiang;  Chen, Jijun; Xu, Dongmei ;*  Wan, Xiaobing* Dual Roles of Sulfonyl Hydrazides: A Three-Component Reaction To Construct Fully Substituted Pyrazoles Using TBAI/TBHP. Org. Lett., 2014, 16, 3312–3315.
6.         Zhang, Feng;  Du, Peng;  Chen, Jijun;  Wang, Hongxiang ;  Luo, QiangWan, Xiaobing,*Co-Catalyzed Synthesis of 1,4-Dicarbonyl Compounds Using TBHP OxidantOrg. Lett., 2014, 16, 19321935.
7.         Chao Zhang, Chunmei Liu, Ying Shao, Xiaoguang Bao,* and Xiaobing Wan,* Nucleophilic Attack of alpha- Aminoalkyl Radicals on Carbon-Nitrogen Triple Bonds to Construct alpha- Amino Nitriles: An Experimental and Computational Study. Chem. Eur. J.2013, 19, 17917–17925.
8.         Jie Zhang, Jiewen Jiang, Yuling Li, and Xiaobing Wan,* Iodide-Catalyzed Synthesis of N-Nitrosamines via C-N Cleavage of Nitromethane. J. Org. Chem.2013, 78, 11366−11372.
9.         Jie Zhang, Jiewen Jiang, Yuling Li, Yun Zhao, and Xiaobing Wan,* A New Strategy for the Construction of alpha-Amino Acid Esters via Decarboxylation. Org. Lett., 2013, 15, 32223225.
10.     Wei Wei, Ying Shao, Huayou Hu, Feng Zhang, Chao Zhang, Yuan Xu, and Xiaobing Wan,* Coupling of Methyl Ketones and Primary or Secondary Amines Leading to α-Ketoamides. J. Org. Chem., 2012, 77, 7157–7165.
11.     Erbo Shi, Ying Shao, Shulin Chen, Huayou Hu, Zhaojun Liu, Jie Zhang, andXiaobing Wan,* Tetrabutylammonium Iodide Catalyzed Synthesis of Allylic Ester with tert-Butyl Hydroperoxide as an Oxidant, Org. Lett., 2012, 14, 3384-3387.
12.     Shulin Chen, Yuan Xu, and Xiaobing Wan,* Direct Condensation of Sulfonamide and Formamide: NaI-Catalyzed Synthesis of N-Sulfonyl Formamidine Using TBHP as Oxidant. Org. Lett., 2011, 13, 6152–6155.
13.     Wei Wei, Chao Zhang, Yuan Xu, Xiaobing Wan,* Synthesis of tert-Butyl Peresters from Aldehydes by Bu4NI-catalyzed Metal-free Oxidation and Its Combination with the Kharasch–Sosnovsky Reaction. Chem. Commun., 2011, 47, 10827-10829.
14.     Hong Li, Yuan Xu, Erbo Shi, Wei Wei, Xiangqiang Suo,Xiaobing Wan,*Synthesis of Arylketones by Ruthenium-Catalyzed Cross-Coupling of Aldehydes with Arylboronic Acids. Chem. Commun., 2011, 47, 7880-7882.
15.     Shulin Chen, Zhaojun Liu, Erbo Shi, Long Chen, Wei Wei, Hong Li, Yannan Cheng, and Xiaobing Wan,*Ruthenium-Catalyzed Oxidation of Alkenes at Room Temperature: A Practical and Concise Approach to α-Diketones.Org. Lett., 2011, 13, 2274-2277.
16.     Long Chen, Erbo Shi, Zhaojun Liu, Shulin Chen, Wei Wei, Hong Li, Kai Xu and Xiaobing Wan,* Bu4NI-Catalyzed C–O Formation via Cross-Dehydrogenative Coupling (CDC) Reaction. Chem. Eur. J.2011, 17, 4085-4089.
17.     Hong Li, Wei Wei, Yuan Xu, Chao Zhang and Xiaobing Wan,* Ru-catalyzed Aerobic Oxidative Coupling of Arylboronic Acids with Arenes. Chem. Commun., 2011, 47, 1497–1499.
18.     Wei Ren, Jinfeng Liu, Long Chen, andXiaobing Wan,* Ruthenium-Catalyzed Alkyne Oxidation with Part-Per-Million Catalyst Loadings Adv. Synth. Catal.2010, 352, 1424–1428.
19.     Wei Ren, Yuanzhi Xia, Shun-Jun Ji, Yong Zhang, Xiaobing Wan,* and Jing Zhao, Wacker-Type Oxidation of Alkynes into 1,2-Diketones Using Molecular Oxygen. Org. Lett., 2009, 11, 1841–1844.