Metal-Free Synthesis of N‑(Carboselenoate) Benzimidazolones by Cascade Cyclization of ortho-Diisocyanoarenes and Selenosulfonates

Yi Fang^†, Can Liu^†, Weidong Rao^‡, Shun-Yi Wang^*,†（汪顺义）, and Shun-Jun Ji^*,†（纪顺俊）

^†Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, and Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou 215123, China

^‡Jiangsu Key Laboratory of Biomass-based Green Fuels and Chemicals, College of Chemical Engineering, Nanjing Forestry University, Nanjing 210037, China

Org. Lett.2019,21, 7687--7691

A facile synthesis of N-(carboselenoate) benzimidazolones through metal-free reactions of ortho-diisocyanoarenes with selenosulfonates is reported here. The desired products are obtained in moderate to good yields with good functional group compatibility. The ortho-diisocyanoarenes are applied to the construction of 2-benzimidazolone derivatives for the first time.

链接：https://pubs.acs.org/doi/10.1021/acs.orglett.9b01886