Polymerization-Induced Self-Assembly Promoted by Liquid−Liquid Phase Separation
Yi Ding, Qingqing Zhao, Lei Wang, Leilei Huang, Qizhou Liu, Xinhua Lu, and Yuanli Cai*(蔡远利)
State-Local Joint Engineering Laboratory for Novel Functional Polymer Materials, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, China
ACS Macro Lett. 2019, 8, 943--946
Polymerization-inducedself-assembly (PISA) is a powerful method for the synthesis of polymeric kinetically frozen core nanoparticles. However, the PISA synthesis of biologically important polymeric fluidic materials is unexplored. Herein we present a liquid–liquidphaseseparation mode PISA. The proof of concept is established by means of complex coacervation in visible light-initiated RAFT dispersion polymerization of anionic monomer in the presence of a protonated polyethylenimine in water at 25 °C. We demonstrate a stage-by-stage nano to micron droplet growth mechanism via an increase in growing chain DP or electrical neutralization. Liquid coacervate droplets and their glassy nanowires or vesicles can be interconverted upon changing the ethanol/water solvent. As such, tunable construction of coacervate droplets and nanowires or vesicles can be achieved using this smart PISA method.
链接:https://pubs.acs.org/doi/abs/10.1021/acsmacrolett.9b00435